Percutaneous vertebroplasty in multiple myeloma vertebral involvement

Salvatore Masala, Giovanni Carlo Anselmetti, Stefano Marcia, Francesco Massari, Antonio Manca, Giovanni Simonetti

Research output: Contribution to journalArticle

Abstract

STUDY DESIGN AND OBJECTIVE: The aim of this study was to assess the effectiveness and safety of percutaneous vertebroplasty, a new technique for the treatment of vertebral pain deriving from fracture or gross osteolytic lesion due to multiple myeloma spinal involvement. SUMMARY OF BACKGROUND DATA: Spinal osteolytic lesions are frequently associated with hematologic malignancies due to primary localization of disease (multiple myeloma and rarely lymphoma) or secondary effect of intensive corticosteroid therapy. METHODS: We treated 64 patients (34 males, 30 females; mean age 71.4±9.6y) with pain refractory to conventional medical therapy (analgesics, bed-rest, bracing with orthopedic devices for more than 3wk) localized in spine, in the absence of neurologic signs. RESULTS: This treatment generated swift pain relief associated with an evident augmentation in vertebral resistance. Average preprocedural pain level for all patients was reported to be 8.04±1.4 whereas average pain level at 1 and 6 months follow-up period was 1.82±1.84 and 1.92±1.68, respectively. Although preprocedure and postprocedure demonstrated a statistically significant reduction in numeric pain scores (P

Original languageEnglish
Pages (from-to)344-348
Number of pages5
JournalJournal of Spinal Disorders and Techniques
Volume21
Issue number5
DOIs
Publication statusPublished - Jul 2008

Keywords

  • Multiple myeloma
  • Spinal hematologic malignancies
  • Vertebral compression fracture
  • Vertebroplasty

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Orthopedics and Sports Medicine

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