Percutaneous vertebroplasty in osteoporotic patients: An institutional experience of 1,634 patients with long-term follow-up

Giovanni Carlo Anselmetti, Antonio Manca, Joshua Hirsch, Filippo Montemurro, Giancarlo Isaia, Giangiacomo Osella, Gabriele Chiara, Gabriella Iussich, Felicino Debernardi, Daniele Regge

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To assess long-term clinical outcome of percutaneous vertebroplasty (PV). Materials and Methods: PV was performed in 1,634 patients (1,387 women; median age 73 years ± 9.3) with painful osteoporotic vertebral compression fractures (VCFs). All patients had back pain that persisted for <2 months with a concordant magnetic resonance imaging study. After PV, medical therapy for osteoporosis was continued, and patients were prospectively evaluated (follow-up 11.844.9 months, mean 25.0 months). Visual analog scale (VAS), Oswestry Disability Index (ODI), analgesic drug use, and use of external brace support were recorded at baseline and during follow-up. New occurrences of symptomatic vertebral fractures were recorded. Results: The mean VAS score of 7.94 significantly improved to 1.12 at the primary endpoint (P 2 = 31.005, P

Original languageEnglish
Pages (from-to)1714-1720
Number of pages7
JournalJournal of Vascular and Interventional Radiology
Volume22
Issue number12
DOIs
Publication statusPublished - Dec 2011

Keywords

  • ODI
  • Oswestry Disability Index
  • percutaneous vertebroplasty
  • PMMA
  • polymethyl methacrylate
  • PV
  • randomized controlled trial
  • RCT
  • VAS
  • VCF
  • vertebral compression fracture
  • visual analogue scale

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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