Percutaneous vs. Surgical placement of hepatic artery indwelling catheters for regional chemotherapy

Luca Aldrighetti, Marcella Arru, Enzo Angeli, Massimo Venturini, Marco Salvioni, Monica Ronzoni, Roberto Caterini, Gianfranco Ferla

Research output: Contribution to journalArticle

Abstract

Background/Aims: Intra-arterial hepatic chemotherapy based on floxuridine infusion is an effective treatment for hepatic metastases from colorectal cancer. The aim of the present study is the comparative analysis of surgical and percutaneous transaxillary approaches to implant a catheter into the hepatic artery for intra-arterial hepatic chemotherapy with floxuridine. Methodology: Fifty-six patients received an arterial device for intra-arterial hepatic chemotherapy. Twenty-eight patients (LPT group) underwent laparotomy to implant the catheter into the hepatic artery, the other 28 patients (PCT group) received a percutaneous catheter into the hepatic artery through a transaxillary percutaneous access. Safety and efficacy of surgical and percutaneous transaxillary approaches were comparatively analyzed in terms of number of intra-arterial hepatic chemotherapy cycles administered, device-related complications causing suppression of intra-arterial hepatic chemotherapy, and biological costs of the procedures. Results: Mean postoperative hospitalization was 8.2±2.2 days in the LPT group and 1.8±0.7 days in the PCT group (P

Original languageEnglish
Pages (from-to)513-517
Number of pages5
JournalHepato-Gastroenterology
Volume49
Issue number44
Publication statusPublished - 2002

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Keywords

  • Arterial devices
  • Comparative study
  • Hepatic chemotherapy
  • Implant techniques

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Aldrighetti, L., Arru, M., Angeli, E., Venturini, M., Salvioni, M., Ronzoni, M., Caterini, R., & Ferla, G. (2002). Percutaneous vs. Surgical placement of hepatic artery indwelling catheters for regional chemotherapy. Hepato-Gastroenterology, 49(44), 513-517.