Perendoscopic real-time assessment of pH improves detection of gastric preneoplastic conditions

G. Pezzicoli, F. A. Tucci, A. Ummarino, P. Tucci, A. P. Di Virgilio, M. Bisceglia, M. Rugge, A. Tucci, A. Andriulli

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Aim. Gastric juice may constitute a precious source of clinicopathological information. We assessed the usefulness of real-time, perendoscopic, gastric juice pH determination in identifying preneoplastic conditions of the stomach, that often escape the mere endoscopic evaluation. Methods. The study included 245 patients (115M; 130F; age 47±17). In each of them perendoscopic gastric juice pH was assessed by means of an innovative device, the Endofaster, and the results were correlated with histological evaluation (H&E, immunohistochemistry, argyrophil stains), and gastric acid secretion (BAO-PAO), and serum gastrin levels. The conditions evaluated were: atrophy, intestinal metaplasia, endocrine cell hyperplasia, hypergastrinemia. Results. A total of 136 pathological conditions were detected and these resulted to be correlated with pH (r=0.67; P

Original languageEnglish
Pages (from-to)97-105
Number of pages9
JournalMinerva Gastroenterologica e Dietologica
Volume59
Issue number1
Publication statusPublished - Mar 2013

Fingerprint

Precancerous Conditions
Gastric Juice
Stomach
Endocrine Cells
Gastric Acid
Gastrins
Metaplasia
Atrophy
Hyperplasia
Coloring Agents
Immunohistochemistry
Equipment and Supplies
Serum

Keywords

  • Gastric juice
  • Gastritis, atrophic
  • Metaplasia

ASJC Scopus subject areas

  • Gastroenterology
  • Internal Medicine
  • Nutrition and Dietetics
  • Endocrinology, Diabetes and Metabolism

Cite this

Pezzicoli, G., Tucci, F. A., Ummarino, A., Tucci, P., Di Virgilio, A. P., Bisceglia, M., ... Andriulli, A. (2013). Perendoscopic real-time assessment of pH improves detection of gastric preneoplastic conditions. Minerva Gastroenterologica e Dietologica, 59(1), 97-105.

Perendoscopic real-time assessment of pH improves detection of gastric preneoplastic conditions. / Pezzicoli, G.; Tucci, F. A.; Ummarino, A.; Tucci, P.; Di Virgilio, A. P.; Bisceglia, M.; Rugge, M.; Tucci, A.; Andriulli, A.

In: Minerva Gastroenterologica e Dietologica, Vol. 59, No. 1, 03.2013, p. 97-105.

Research output: Contribution to journalArticle

Pezzicoli, G, Tucci, FA, Ummarino, A, Tucci, P, Di Virgilio, AP, Bisceglia, M, Rugge, M, Tucci, A & Andriulli, A 2013, 'Perendoscopic real-time assessment of pH improves detection of gastric preneoplastic conditions', Minerva Gastroenterologica e Dietologica, vol. 59, no. 1, pp. 97-105.
Pezzicoli G, Tucci FA, Ummarino A, Tucci P, Di Virgilio AP, Bisceglia M et al. Perendoscopic real-time assessment of pH improves detection of gastric preneoplastic conditions. Minerva Gastroenterologica e Dietologica. 2013 Mar;59(1):97-105.
Pezzicoli, G. ; Tucci, F. A. ; Ummarino, A. ; Tucci, P. ; Di Virgilio, A. P. ; Bisceglia, M. ; Rugge, M. ; Tucci, A. ; Andriulli, A. / Perendoscopic real-time assessment of pH improves detection of gastric preneoplastic conditions. In: Minerva Gastroenterologica e Dietologica. 2013 ; Vol. 59, No. 1. pp. 97-105.
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