Perforation in colorectal stenting: A meta-analysis and a search for risk factors

Emo E. Van Halsema, Jeanin E. Van Hooft, Aaron J. Small, Todd H. Baron, Jesús García-Cano, Jae Hee Cheon, Moon Sung Lee, Se Hwan Kwon, Stéphanie Mucci-Hennekinne, Paul Fockens, Marcel G W Dijkgraaf, Alessandro Repici

Research output: Contribution to journalArticlepeer-review


Background Recent studies suggest that there is a substantial risk of perforation after colorectal stent placement. Objective To identify risk factors for perforation from colonic stenting. Design A meta-analysis of 86 studies published between 2005 and 2011. Setting Multicenter review. Patients All patients who underwent colorectal stent placement. Intervention Colorectal stent placement. Main Outcome Measurements The occurrence of perforation with subgroup analyses for stent design, stricture etiology, stricture dilation, and concomitant chemotherapy, including the use of bevacizumab. Results A total of 4086 patients underwent colorectal stent placement; perforation occurred in 207. Meta-analysis revealed an overall perforation rate of 7.4%. Of the 9 most frequently used stent types, the WallFlex, the Comvi, and the Niti-S D-type had a higher perforation rate (>10%). A lower perforation rate (

Original languageEnglish
JournalGastrointestinal Endoscopy
Issue number6
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Gastroenterology
  • Radiology Nuclear Medicine and imaging
  • Medicine(all)


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