Comportamento angiografico perinfartuale delle lesioni coronariche "non colpevoli" di infarto.

Translated title of the contribution: Peri-infarct angiographic behavior of "non-culprit" coronary infarct lesions

A. Loaldi, M. Bussotti, L. Grancini, M. Guazzi, I. L. Pera, N. B. de Cesare

Research output: Contribution to journalArticle

Abstract

Because systemic factors, such as lipoproteins, autoantigens, infectious agents, may facilitate plaque rupture, thrombus formation and coronary occlusion, the question may arise of whether thrombosis be only a local plaque event or the consequence of an acute activity of the entire coronary tree. Taking changes at the narrowest point of non culprit lesions as reflecting progression or regression of the disease when > 0.27 mm, early (within a few days) and late (within 1 month) coronarographic findings in 23 patients with first infarction were compared with those of patients with stable angina, in whom coronary angiography was performed for diagnostic purposes and was repeated 1 month later, before angioplasty. Sixteen infarction patients had progression, 4 had regression, 1 had both, and 2 had steadiness; corresponding values in stable angina group were 2 (p <0.001), 1 (NS), 0 (NS) and 20 (p <0.001). In the infarction group, 17 out of the 45 non culprit lesions progressed and 5 regressed; corresponding figures in stable angina group were 2 (p <0.001) and 1 (p <0.05). Three of the infarction patients developed interim angina at rest that was associated with progression of a culprit lesion in each of them. These results support the hypothesis that in a number of cases infarction may not reflect an arbitrary plaque event but rather a systemic coronary disease activity with maximal expression at the level of the offending plaque.

Original languageItalian
Pages (from-to)1153-1158
Number of pages6
JournalCardiologia
Volume42
Issue number11
Publication statusPublished - Nov 1997

Fingerprint

Infarction
Stable Angina
Thrombosis
Coronary Occlusion
Unstable Angina
Autoantigens
Coronary Angiography
Angioplasty
Lipoproteins
Coronary Disease
Rupture

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Comportamento angiografico perinfartuale delle lesioni coronariche "non colpevoli" di infarto. / Loaldi, A.; Bussotti, M.; Grancini, L.; Guazzi, M.; Pera, I. L.; de Cesare, N. B.

In: Cardiologia, Vol. 42, No. 11, 11.1997, p. 1153-1158.

Research output: Contribution to journalArticle

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