Perianal and intrarectal anaesthesia for transrectal biopsy of the prostate: A prospective randomized study comparing lidocaine-prilocaine cream and placebo

Marco Raber, Vincenzo Scattoni, Marco Roscigno, Patrizio Rigahi, Francesco Montorsi

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To assess the effectiveness of perianal and intrarectal lidocaine-prilocaine cream for prostate biopsy. PATIENTS AND METHODS: In a prospective, randomized, double-blind, placebo-controlled study, 200 consecutive patients were randomized to receive 5 mL lidocaine-prilocaine cream or 5 mL placebo peri-anally and transrectally before transrectal ultrasonography (TRUS)-guided prostate needle biopsy (mean number of cores, 12). The men were asked to grade the pain when the TRUS probe was inserted and during the biopsy procedure using a 10-point linear visual analogue pain scale. RESULTS: At probe insertion, men in the anaesthetic group reported a significantly lower mean pain level than men in the placebo group (0.3 vs 1.6, P <0.001). Men who had anaesthetic also reported less pain during biopsy punctures (1.8 vs 3.2, P <0.001). Stratifying results by age, younger men (

Original languageEnglish
Pages (from-to)1264-1267
Number of pages4
JournalBJU International
Volume96
Issue number9
DOIs
Publication statusPublished - Dec 2005

Keywords

  • Biopsy
  • Local anaesthesia
  • Prostate cancer

ASJC Scopus subject areas

  • Urology

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