Perinatal outcome in HIV-infected pregnant women

A. E. Semprini, M. Ravizza, A. Bucceri, A. Vucetich, G. Pardi

Research output: Contribution to journalArticle

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Abstract

We have observed 74 HIV-seropositive and 48 HIV-seronegative drug-addicted women and 22 HIV-seropositive nondrug-addicted pregnant women during pregnancy and we report their perinatal outcome. 8 out of 96 HIV-seropositive patients had hematological signs of immunodeficiency and 2 of these patients were symptomatic belonging to CDC class III. We recorded 2 early and 3 late spontaneous abortions, no intrauterine fetal death and 3 neonatal deaths. Seropositive patients had 3 malformed babies, seronegative patients had 1. All these women had a high incidence of premature delivery and intrauterine fetal growth retardation: seropositive patients had a higher incidence of fetuses small for gestational age and a lower incidence of preterm delivery compared to seronegative patients, but the difference was not statistically significant. The incidence of malformation was comparable to the general population: 3 malformed babies were born to HIV-positive drug-addicted mothers, and 1 to a seronegative drug-addicted mother. These findings do not support the hypothesis of a direct detrimental effect of HIV on perinatal outcome. Consequences of fetal exposure to maternal HIV infection involve mostly postnatal life and development of acquired immunodeficiency.

Original languageEnglish
Pages (from-to)15-18
Number of pages4
JournalGynecologic and Obstetric Investigation
Volume30
Issue number1
Publication statusPublished - 1990

Fingerprint

Pregnant Women
HIV
Fetal Growth Retardation
Incidence
Mothers
Wiskott-Aldrich Syndrome
Pharmaceutical Preparations
Maternal Exposure
Fetal Death
Spontaneous Abortion
Centers for Disease Control and Prevention (U.S.)
Gestational Age
HIV Infections
Fetus
Pregnancy
Population

Keywords

  • AIDS
  • drug addiction
  • HIV
  • perinatal outcome
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Semprini, A. E., Ravizza, M., Bucceri, A., Vucetich, A., & Pardi, G. (1990). Perinatal outcome in HIV-infected pregnant women. Gynecologic and Obstetric Investigation, 30(1), 15-18.

Perinatal outcome in HIV-infected pregnant women. / Semprini, A. E.; Ravizza, M.; Bucceri, A.; Vucetich, A.; Pardi, G.

In: Gynecologic and Obstetric Investigation, Vol. 30, No. 1, 1990, p. 15-18.

Research output: Contribution to journalArticle

Semprini, AE, Ravizza, M, Bucceri, A, Vucetich, A & Pardi, G 1990, 'Perinatal outcome in HIV-infected pregnant women', Gynecologic and Obstetric Investigation, vol. 30, no. 1, pp. 15-18.
Semprini AE, Ravizza M, Bucceri A, Vucetich A, Pardi G. Perinatal outcome in HIV-infected pregnant women. Gynecologic and Obstetric Investigation. 1990;30(1):15-18.
Semprini, A. E. ; Ravizza, M. ; Bucceri, A. ; Vucetich, A. ; Pardi, G. / Perinatal outcome in HIV-infected pregnant women. In: Gynecologic and Obstetric Investigation. 1990 ; Vol. 30, No. 1. pp. 15-18.
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