Periodic alternating nystagmus and vestibulo-spinal system facilitating activity

M. Versino, A. Romani, R. Callieco, E. Alfonsi, G. Beltrami, M. Manfrin, V. Cosi

Research output: Contribution to journalArticlepeer-review


Objective: Periodic alternating nystagmus has been associated with the instability of the velocity storage mechanism, which is known to play an important role in both the vestibulo-oculomotor and the optokinetic systems. In the present study we looked for a possible spinal equivalent to PAN. Methods and results: In 3 PAN patients, the H-reflex amplitude proved to be slightly but significantly influenced by nystagmus direction, in that it was greater when the nystagmus was beating toward the stimulation side. Conclusions: This finding suggests that projections from velocity storage may play a role not only in the ocular motor but also in assisting postural stability through the vestibulo-spinal system. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)1337-1339
Number of pages3
JournalClinical Neurophysiology
Issue number8
Publication statusPublished - Aug 1 2000


  • H-reflex
  • Periodic alternating nystagmus
  • Postural stability
  • Velocity storage

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems


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