Periodontal Disease: An Oral Manifestation of Psoriasis or an Occasional Finding?

Giulia Ganzetti, Anna Campanati, Andrea Santarelli, Valentina Pozzi, Elisa Molinelli, Ilaria Minnetti, Valerio Brisigotti, Maurizio Procaccini, Monica Emanuelli, Annamaria Offidani

Research output: Contribution to journalArticlepeer-review


Postmarketing Phase IV Even if the existence of oral psoriasis has been suggested, it is still a debated issue. Indeed, oral inflammatory diseases may histologically resemble psoriasis-related oral lesions. However, an increased prevalence of fissured tongue and geographic tongue has been associated with psoriatic patients, being a transitory and permanent lesion, respectively. Recently, it was hypothesized that gingivitis and periodontitis share the same underlying inflammatory pathogenetic process of psoriasis. Thus, in the present study, psoriatic patients were investigated for oral mucosa lesions prevalence as well as gum disease. Results displayed an increased association between gingivitis/periodontitis and psoriasis, which may suggest common underlying pathogenic risk factors. However, large-scale studies are needed to evaluate the real prevalence of gingivitis and periodontitis in these patients, to consider them a comorbidity of psoriasis.

Original languageEnglish
Pages (from-to)S46-S49
JournalDrug Development Research
Publication statusPublished - 2014


  • inflammatory pathogenesis
  • oral pathology
  • periodontal disease
  • psoriasis

ASJC Scopus subject areas

  • Drug Discovery
  • Medicine(all)


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