TY - JOUR
T1 - Periodontal Disease
T2 - An Oral Manifestation of Psoriasis or an Occasional Finding?
AU - Ganzetti, Giulia
AU - Campanati, Anna
AU - Santarelli, Andrea
AU - Pozzi, Valentina
AU - Molinelli, Elisa
AU - Minnetti, Ilaria
AU - Brisigotti, Valerio
AU - Procaccini, Maurizio
AU - Emanuelli, Monica
AU - Offidani, Annamaria
PY - 2014
Y1 - 2014
N2 - Postmarketing Phase IV Even if the existence of oral psoriasis has been suggested, it is still a debated issue. Indeed, oral inflammatory diseases may histologically resemble psoriasis-related oral lesions. However, an increased prevalence of fissured tongue and geographic tongue has been associated with psoriatic patients, being a transitory and permanent lesion, respectively. Recently, it was hypothesized that gingivitis and periodontitis share the same underlying inflammatory pathogenetic process of psoriasis. Thus, in the present study, psoriatic patients were investigated for oral mucosa lesions prevalence as well as gum disease. Results displayed an increased association between gingivitis/periodontitis and psoriasis, which may suggest common underlying pathogenic risk factors. However, large-scale studies are needed to evaluate the real prevalence of gingivitis and periodontitis in these patients, to consider them a comorbidity of psoriasis.
AB - Postmarketing Phase IV Even if the existence of oral psoriasis has been suggested, it is still a debated issue. Indeed, oral inflammatory diseases may histologically resemble psoriasis-related oral lesions. However, an increased prevalence of fissured tongue and geographic tongue has been associated with psoriatic patients, being a transitory and permanent lesion, respectively. Recently, it was hypothesized that gingivitis and periodontitis share the same underlying inflammatory pathogenetic process of psoriasis. Thus, in the present study, psoriatic patients were investigated for oral mucosa lesions prevalence as well as gum disease. Results displayed an increased association between gingivitis/periodontitis and psoriasis, which may suggest common underlying pathogenic risk factors. However, large-scale studies are needed to evaluate the real prevalence of gingivitis and periodontitis in these patients, to consider them a comorbidity of psoriasis.
KW - inflammatory pathogenesis
KW - oral pathology
KW - periodontal disease
KW - psoriasis
UR - http://www.scopus.com/inward/record.url?scp=84910069371&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84910069371&partnerID=8YFLogxK
U2 - 10.1002/ddr.21194
DO - 10.1002/ddr.21194
M3 - Article
C2 - 25381976
AN - SCOPUS:84910069371
VL - 75
SP - S46-S49
JO - Drug Development Research
JF - Drug Development Research
SN - 0272-4391
ER -