TY - JOUR
T1 - Periodontal regeneration in aggressive periodontitis patients
T2 - A systematic review of the literature
AU - Corbella, Stefano
AU - Weinstein, Roberto
AU - Francetti, Luca
AU - Taschieri, Silvio
AU - Del Fabbro, Massimo
N1 - © 2016 John Wiley & Sons Australia, Ltd.
PY - 2017/11
Y1 - 2017/11
N2 - The aim of the present study was to systematically review the existing literature on periodontal regenerative procedures in individuals affected by aggressive periodontitis (AgP). An electronic and manual search was performed using an ad hoc prepared search string. All types of study designs were considered acceptable for inclusion. Data about treated patients, baseline clinical parameters, type of surgery, and outcomes were extracted and recorded. A narrative evaluation of the results was performed. After the article-selection process, a total of 22 full-texts were included in the qualitative synthesis. Twelve papers were case reports; one was a retrospective study; six were non-randomized, comparative studies; and three papers were published on two randomized, controlled trials (RCT). Various biomaterials and surgical techniques were described in the included papers. Based on the existing literature, even considering the relatively low level of evidence, periodontal regenerative surgery could be successfully performed in patients affected by AgP. There is a substantial need of high-quality RCT to support this.
AB - The aim of the present study was to systematically review the existing literature on periodontal regenerative procedures in individuals affected by aggressive periodontitis (AgP). An electronic and manual search was performed using an ad hoc prepared search string. All types of study designs were considered acceptable for inclusion. Data about treated patients, baseline clinical parameters, type of surgery, and outcomes were extracted and recorded. A narrative evaluation of the results was performed. After the article-selection process, a total of 22 full-texts were included in the qualitative synthesis. Twelve papers were case reports; one was a retrospective study; six were non-randomized, comparative studies; and three papers were published on two randomized, controlled trials (RCT). Various biomaterials and surgical techniques were described in the included papers. Based on the existing literature, even considering the relatively low level of evidence, periodontal regenerative surgery could be successfully performed in patients affected by AgP. There is a substantial need of high-quality RCT to support this.
U2 - 10.1111/jicd.12245
DO - 10.1111/jicd.12245
M3 - Review article
C2 - 27778470
VL - 8
JO - Journal of investigative and clinical dentistry
JF - Journal of investigative and clinical dentistry
SN - 2041-1618
IS - 4
ER -