Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery

Pasquale Florio; Raul Felipe Abella; Teresa De La Torre; Alessandro Giamberti; Stefano Luisi; Gianfranco Butera; Alessandro Cazzaniga; Alessandro Frigiola; Felice Petraglia; Diego Gazzolo

doi:10.1373/clinchem.2006.077149

Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery

Pasquale Florio, Raul Felipe Abella, Teresa De La Torre, Alessandro Giamberti, Stefano Luisi, Gianfranco Butera, Alessandro Cazzaniga, Alessandro Frigiola, Felice Petraglia, Diego Gazzolo

IRCCS Policlinico San Donato

Research output: Contribution to journal › Article

Abstract

Background: Ischemic-reperfusion injury of the brain is a major adverse event after cardiac surgery, especially when extracorporeal circuits are used. Because brain injury induces local overproduction of activin A, we measured plasma concentrations in children after open heart surgery with cardiopulmonary bypass (CPB) to investigate the potential of measuring activin A for early identification of infants at risk for brain damage. Methods: We evaluated 45 infants (age

Original language	English
Pages (from-to)	982-985
Number of pages	4
Journal	Clinical Chemistry
Volume	53
Issue number	5
DOIs	https://doi.org/10.1373/clinchem.2006.077149
Publication status	Published - May 2007

ASJC Scopus subject areas

Clinical Biochemistry

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Florio, P., Abella, R. F., De La Torre, T., Giamberti, A., Luisi, S., Butera, G., Cazzaniga, A., Frigiola, A., Petraglia, F., & Gazzolo, D. (2007). Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery. Clinical Chemistry, 53(5), 982-985. https://doi.org/10.1373/clinchem.2006.077149

Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery. / Florio, Pasquale; Abella, Raul Felipe; De La Torre, Teresa; Giamberti, Alessandro; Luisi, Stefano; Butera, Gianfranco; Cazzaniga, Alessandro; Frigiola, Alessandro; Petraglia, Felice; Gazzolo, Diego.

In: Clinical Chemistry, Vol. 53, No. 5, 05.2007, p. 982-985.

Research output: Contribution to journal › Article

Florio, Pasquale ; Abella, Raul Felipe ; De La Torre, Teresa ; Giamberti, Alessandro ; Luisi, Stefano ; Butera, Gianfranco ; Cazzaniga, Alessandro ; Frigiola, Alessandro ; Petraglia, Felice ; Gazzolo, Diego. / Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery. In: Clinical Chemistry. 2007 ; Vol. 53, No. 5. pp. 982-985.

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