Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery

Pasquale Florio, Raul Felipe Abella, Teresa De La Torre, Alessandro Giamberti, Stefano Luisi, Gianfranco Butera, Alessandro Cazzaniga, Alessandro Frigiola, Felice Petraglia, Diego Gazzolo

Research output: Contribution to journalArticle

Abstract

Background: Ischemic-reperfusion injury of the brain is a major adverse event after cardiac surgery, especially when extracorporeal circuits are used. Because brain injury induces local overproduction of activin A, we measured plasma concentrations in children after open heart surgery with cardiopulmonary bypass (CPB) to investigate the potential of measuring activin A for early identification of infants at risk for brain damage. Methods: We evaluated 45 infants (age

Original languageEnglish
Pages (from-to)982-985
Number of pages4
JournalClinical Chemistry
Volume53
Issue number5
DOIs
Publication statusPublished - May 2007

ASJC Scopus subject areas

  • Clinical Biochemistry

Fingerprint Dive into the research topics of 'Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery'. Together they form a unique fingerprint.

  • Cite this