TY - JOUR
T1 - Perioperative activin A concentrations as a predictive marker of neurologic abnormalities in children after open heart surgery
AU - Florio, Pasquale
AU - Abella, Raul Felipe
AU - De La Torre, Teresa
AU - Giamberti, Alessandro
AU - Luisi, Stefano
AU - Butera, Gianfranco
AU - Cazzaniga, Alessandro
AU - Frigiola, Alessandro
AU - Petraglia, Felice
AU - Gazzolo, Diego
PY - 2007/5
Y1 - 2007/5
N2 - Background: Ischemic-reperfusion injury of the brain is a major adverse event after cardiac surgery, especially when extracorporeal circuits are used. Because brain injury induces local overproduction of activin A, we measured plasma concentrations in children after open heart surgery with cardiopulmonary bypass (CPB) to investigate the potential of measuring activin A for early identification of infants at risk for brain damage. Methods: We evaluated 45 infants (age
AB - Background: Ischemic-reperfusion injury of the brain is a major adverse event after cardiac surgery, especially when extracorporeal circuits are used. Because brain injury induces local overproduction of activin A, we measured plasma concentrations in children after open heart surgery with cardiopulmonary bypass (CPB) to investigate the potential of measuring activin A for early identification of infants at risk for brain damage. Methods: We evaluated 45 infants (age
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U2 - 10.1373/clinchem.2006.077149
DO - 10.1373/clinchem.2006.077149
M3 - Article
C2 - 17363421
AN - SCOPUS:34248334517
VL - 53
SP - 982
EP - 985
JO - Clinical Chemistry
JF - Clinical Chemistry
SN - 0009-9147
IS - 5
ER -