Abstract
The evolution of scientific knowledge in cardiac surgery and cardiopulmonary bypass has enabled the reduction of perioperative complications, despite an increase in patient-related risks and in the complexity of surgical procedures. However, the management of hemostasis and coagulation remains a difficult issue, and it is of note that the rates of allogeneic blood transfusion and surgical revision in bleeding patients have not declined in recent years. The perioperative coagulopathy in patients undergoing cardiac surgical procedures is a highly complex and challenging field, and appropriate management is essential to improve morbidity and mortality. Identifying the patient’s preoperative hemorrhagic risk factors and understanding the mechanisms involved in coagulopathy and fibrinolysis during cardiopulmonary bypass are crucial for the patient’s care. Today, the use of practice guidelines and point-of-care testing is an established part of the management of the bleeding patient. In this chapter, we review the state of knowledge on perioperative hemostasis management in cardiac surgery and describe some specific points on the pathophysiology and pharmacology of CPB-related coagulopathies.
| Original language | English |
|---|---|
| Title of host publication | Perioperative Hemostasis: Coagulation for Anesthesiologists |
| Publisher | Springer Berlin Heidelberg |
| Pages | 243-266 |
| Number of pages | 24 |
| ISBN (Print) | 9783642550041, 9783642550034 |
| DOIs | |
| Publication status | Published - Jan 1 2015 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Perioperative coagulation in cardiovascular surgery. / Gronchi, Fabrizio; Ranucci, Marco.
Perioperative Hemostasis: Coagulation for Anesthesiologists. Springer Berlin Heidelberg, 2015. p. 243-266.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Perioperative coagulation in cardiovascular surgery
AU - Gronchi, Fabrizio
AU - Ranucci, Marco
PY - 2015/1/1
Y1 - 2015/1/1
N2 - The evolution of scientific knowledge in cardiac surgery and cardiopulmonary bypass has enabled the reduction of perioperative complications, despite an increase in patient-related risks and in the complexity of surgical procedures. However, the management of hemostasis and coagulation remains a difficult issue, and it is of note that the rates of allogeneic blood transfusion and surgical revision in bleeding patients have not declined in recent years. The perioperative coagulopathy in patients undergoing cardiac surgical procedures is a highly complex and challenging field, and appropriate management is essential to improve morbidity and mortality. Identifying the patient’s preoperative hemorrhagic risk factors and understanding the mechanisms involved in coagulopathy and fibrinolysis during cardiopulmonary bypass are crucial for the patient’s care. Today, the use of practice guidelines and point-of-care testing is an established part of the management of the bleeding patient. In this chapter, we review the state of knowledge on perioperative hemostasis management in cardiac surgery and describe some specific points on the pathophysiology and pharmacology of CPB-related coagulopathies.
AB - The evolution of scientific knowledge in cardiac surgery and cardiopulmonary bypass has enabled the reduction of perioperative complications, despite an increase in patient-related risks and in the complexity of surgical procedures. However, the management of hemostasis and coagulation remains a difficult issue, and it is of note that the rates of allogeneic blood transfusion and surgical revision in bleeding patients have not declined in recent years. The perioperative coagulopathy in patients undergoing cardiac surgical procedures is a highly complex and challenging field, and appropriate management is essential to improve morbidity and mortality. Identifying the patient’s preoperative hemorrhagic risk factors and understanding the mechanisms involved in coagulopathy and fibrinolysis during cardiopulmonary bypass are crucial for the patient’s care. Today, the use of practice guidelines and point-of-care testing is an established part of the management of the bleeding patient. In this chapter, we review the state of knowledge on perioperative hemostasis management in cardiac surgery and describe some specific points on the pathophysiology and pharmacology of CPB-related coagulopathies.
UR - http://www.scopus.com/inward/record.url?scp=84955751838&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955751838&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-55004-1_14
DO - 10.1007/978-3-642-55004-1_14
M3 - Chapter
AN - SCOPUS:84955751838
SN - 9783642550041
SN - 9783642550034
SP - 243
EP - 266
BT - Perioperative Hemostasis: Coagulation for Anesthesiologists
PB - Springer Berlin Heidelberg
ER -