Peripheral blood markers of inflammation and functional impairment in elderly community-dwellers

G. Ravaglia, P. Forti, F. Maioli, N. Brunetti, M. Martelli, T. Talerico, L. Bastagli, A. Muscari, E. Mariani

Research output: Contribution to journalArticlepeer-review


The cross-sectional association of functional impairment with several peripheral blood inflammatory markers (increased C-reactive protein (CRP), fibrinogen and leucocyte count, decreased cholesterol and albumin) was studied in 739 elderly community-dwellers. Functional measures included Tinetti test for gait and balance, and basic and Instrumental Activities of Daily Living. When considering each marker individually, only increased CRP was inversely associated with all functional measures independently of demographics, lifestyle, and comorbidity (P0.05), or other positive markers alone or in combination (P

Original languageEnglish
Pages (from-to)1415-1422
Number of pages8
JournalExperimental Gerontology
Issue number9
Publication statusPublished - Sep 2004


  • Disability
  • Elderly
  • Functional impairment
  • Inflammation
  • Physical performance
  • Serum C-reactive protein

ASJC Scopus subject areas

  • Ageing
  • Medicine(all)


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