Abstract
Peripheral microcirculation was studied in digital biopsies of 8 patients affected by Steinert's disease and in 5 normal volunteers. In 5 patients in whom clinical and laboratory investigations exclude diabetes, hypertension and other angiopathy-inducing disease, light and electron microscopic studies demonstrated significant thickening of the capillary basement membrane similar to that observed in diabetic microangiopathy, and haemodynamic-proliferative arteriosclerotic changes in arterioles and arteriovenular anastomoses, unrelated to the young age of the patients. Statistical evaluations revealed a significant correlation between peripheral microvascular alterations and disease duration.
Original language | English |
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Pages (from-to) | 137-148 |
Number of pages | 12 |
Journal | Acta Neurologica |
Volume | 33 |
Issue number | 2 |
Publication status | Published - 1978 |
ASJC Scopus subject areas
- Clinical Neurology