Peripheral Nerve Field Stimulation (PNFS) as a Treatment Option for Intractable Radiation-Induced Facial Neuropathic Pain in a Survivor of Laryngeal Cancer: A Case Report

Vincenzo Levi, Giuseppe Messina, Angelo Franzini, Luca Zanin, Nicolo Castelli, Ivano Dones

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Treatment-related chronic neuropathic pain represents a major and increasing cause of discomfort in cancer survivors. Unfortunately, in approximately 10%-15% of cases, pain is scarcely relieved by opioids and common painkillers. Thus, alternative measures to manage pain have recently been adopted in these patients. Case Description: We report the case of a laryngeal cancer survivor who developed an intractable bilateral mandibular radiation-induced neuropathic pain syndrome. His pain was refractory to any pharmacological treatment, whereas the implant of bilateral subcutaneous facial electrodes led to the complete resolution of pain. Conclusions: To the best of our knowledge, this is the first report in literature describing peripheral nerve field stimulation as a treatment option for intractable cancer treatment-related chronic neuropathic pain. Peripheral nerve field stimulation appears to be a safe and effective procedure.

Original languageEnglish
JournalWorld Neurosurgery
DOIs
Publication statusAccepted/In press - Jan 28 2016

Keywords

  • Cancer treatment-related pain
  • Neuromodulation
  • Peripheral nerve field stimulation (PNFS)

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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