NEUROPATIA PERIFERICA E FARMACI ANTIEPILETTICI: STUDIO CLINICO ED ELETTROFISIOLOGICO DI 70 PAZIENTI IN MONOTERAPIA

Translated title of the contribution: Peripheral neuropathy and antiepileptic drugs: A clinical and electrophysiological study of 70 patients on monotherapy

G. Bogliun, A. Bono, N. Curto, L. Marzorati, E. Beghi

Research output: Contribution to journalArticlepeer-review

Abstract

A total of 70 adult patients with epilepsy were included as being treated for no less than six months with one of the above: CBZ and PB, 20; PHT, 18; SV, 12. Each patient was investigated through history taking, physical examination and neurophysiological evaluation of the median, ulnar, sural and peroneal nerves using standardized methods. A diagnosis of polyneuropathy (PN) was made when electrophysiologic signs of peripheral nerve involvement were present in two or more nerves. Thirthy-two patients (45%) fulfilled the diagnostic criteria for PN and presented signs of sensory-motor lesion, with predominant involmement of the lower limbs and concurrent demyelinating and axonal damage, although all the drugs were implicated, abnormalities were found to a lesser extent among SV users.

Translated title of the contributionPeripheral neuropathy and antiepileptic drugs: A clinical and electrophysiological study of 70 patients on monotherapy
Original languageItalian
Pages (from-to)349-350
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number70-71
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Clinical Neurology

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