Linfoma a cellule T periferiche con associata sindrome emofagocitica: un'entità di recente identificazione. Studio clinico-patologico ed immunoistochimico di due casi.

Translated title of the contribution: Peripheral T-cell lymphoma associated with hemophagocytic syndrome: a recently identified entity. Clinico-pathologic and immunohistochemical study of 2 cases

A. Saragoni, B. Falini, L. Medri, M. Gaudio, R. Brizio, S. Poggi, E. Sabattini, S. Pileri

Research output: Contribution to journalArticlepeer-review

Abstract

The authors report on two examples of peripheral T-cell lymphoma associated with hemophagocytic syndrome. The latter represents a recently described entity, which is characterized by pancytopenia, hepatosplenomegaly, fever and rapid downhill clinical course. Microscopic examination of different tissue samples shows bone-marrow, liver and spleen infiltration by small-medium sized lymphoid elements, which display peripheral T-cell phenotype and are associated with an exuberant hyperplasia of hemophagocytosing, benign-looking histiocytes. The clinical and pathological findings, along with the main differential diagnoses, are discussed.

Translated title of the contributionPeripheral T-cell lymphoma associated with hemophagocytic syndrome: a recently identified entity. Clinico-pathologic and immunohistochemical study of 2 cases
Original languageItalian
Pages (from-to)359-369
Number of pages11
JournalPathologica
Volume82
Issue number1080
Publication statusPublished - Jul 1990

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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