Periprocedural management of antithrombotic therapy and open issues in cancer patients

A. Cuomo, M. Cascella, F. Bifulco, M. Marracino, G. Di Minno, A. M. Cerbone

Research output: Contribution to journalArticlepeer-review


Perioperative management of patients who are receiving anticoagulant or antiplatelet drugs and require surgical or invasive procedure is a dilemma for clinicians. The discontinuation exposes the patient to an exceedingly high risk of thromboembolism while there is an exceedingly high bleeding risk if antithrombotic therapy is continued, strictly related to the type of surgery. This complex management is based on the assessment of thromboembolic and bleeding risk. In this review we analyze the strategies to optimize the perioperative use of antithrombotic drugs with special attention to new oral anticoagulant drugs, also in cancer patients.

Original languageEnglish
Pages (from-to)1229-1243
Number of pages15
JournalMinerva Anestesiologica
Issue number11
Publication statusPublished - Nov 1 2015


  • Anticoagulants
  • General Surgery
  • Neoplasms

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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