Abstract
Aim: In paediatric and adult patients with neurogenic bowel, transanal irrigation (TAI) of the colon has gained popularity due to the introduction of a specifically designed device. The aim of this pilot study was to present the results of TAI using the Peristeen® TAI system in a group of paediatric patients with anorectal malformation (ARM) and congenital or acquired spinal cord lesions (SCLs). Method: Eight Italian paediatric surgery and spina bifida centres participated in the study. The inclusion criteria were age between 6 and 17 years, weight above 20 kg and unsatisfactory bowel management. Patients with chronic inflammatory bowel disease, mental disability and surgery within the previous 3 months were excluded. At the beginning of treatment (T0) and after 3 months (T1) the Bristol scale, a questionnaire assessing bowel function, and two questionnaires on quality of life (QoL) for patients aged 6-11 years (CHQ-pf50) and 12-17 years (SF36) were administered. Results: Eighty-three patients were enrolled, and seventy-eight completed the study (41 ARMs, 37 SCLs). At T1, constipation was reduced in ARMs from 69% to 25.6% and in SCLs from 92.7% to 41.5%, faecal incontinence in ARMs from 50% to 18.6% and in SCLs from 39% to 9.8% and flatus incontinence in ARMs from 20.9% to 9.8% and in SCLs from 31.7% to 10%. At T0, the Bristol Stool Scale types were 1-2 in 45% of ARMs and 77.5% of SCL patients, whereas at T1 types 1-2 were recorded in only 2.5% of SCL patients. QoL improved in both groups. In the younger group, a significant improvement in QoL was recorded in ARM patients for eight of nine variables and in SCL patients for seven of nine variables. Conclusion: This study showed that Peristeen TAI resulted in a significant time reduction in colonic cleansing, increased independence from the carer and improved QoL in paediatric patients with ARMs and SCLs.
| Original language | English |
|---|---|
| Pages (from-to) | 86-93 |
| Number of pages | 8 |
| Journal | Colorectal Disease |
| Volume | 18 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2016 |
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Keywords
- Anorectal malformation
- Bowel dysfunction
- Enema
- Peristeen
- Spinal cord injuries
- Transanal irrigation
ASJC Scopus subject areas
- Gastroenterology
Cite this
Peristeen® transanal irrigation in paediatric patients with anorectal malformations and spinal cord lesions : A multicentre Italian study. / Midrio, Paola; Mosiello, Giovanni; Ausili, E.; Gamba, Piergiorgio; Marte, Antonio; Lombardi, L.; Iacobelli, Barbara Daniela; Caponcelli, Enrica; Marrello, Saverio; Meroni, M.; Brisighelli, G.; Leva, Ernesto; Rendeli, Claudia.
In: Colorectal Disease, Vol. 18, No. 1, 01.01.2016, p. 86-93.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peristeen® transanal irrigation in paediatric patients with anorectal malformations and spinal cord lesions
T2 - A multicentre Italian study
AU - Midrio, Paola
AU - Mosiello, Giovanni
AU - Ausili, E.
AU - Gamba, Piergiorgio
AU - Marte, Antonio
AU - Lombardi, L.
AU - Iacobelli, Barbara Daniela
AU - Caponcelli, Enrica
AU - Marrello, Saverio
AU - Meroni, M.
AU - Brisighelli, G.
AU - Leva, Ernesto
AU - Rendeli, Claudia
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Aim: In paediatric and adult patients with neurogenic bowel, transanal irrigation (TAI) of the colon has gained popularity due to the introduction of a specifically designed device. The aim of this pilot study was to present the results of TAI using the Peristeen® TAI system in a group of paediatric patients with anorectal malformation (ARM) and congenital or acquired spinal cord lesions (SCLs). Method: Eight Italian paediatric surgery and spina bifida centres participated in the study. The inclusion criteria were age between 6 and 17 years, weight above 20 kg and unsatisfactory bowel management. Patients with chronic inflammatory bowel disease, mental disability and surgery within the previous 3 months were excluded. At the beginning of treatment (T0) and after 3 months (T1) the Bristol scale, a questionnaire assessing bowel function, and two questionnaires on quality of life (QoL) for patients aged 6-11 years (CHQ-pf50) and 12-17 years (SF36) were administered. Results: Eighty-three patients were enrolled, and seventy-eight completed the study (41 ARMs, 37 SCLs). At T1, constipation was reduced in ARMs from 69% to 25.6% and in SCLs from 92.7% to 41.5%, faecal incontinence in ARMs from 50% to 18.6% and in SCLs from 39% to 9.8% and flatus incontinence in ARMs from 20.9% to 9.8% and in SCLs from 31.7% to 10%. At T0, the Bristol Stool Scale types were 1-2 in 45% of ARMs and 77.5% of SCL patients, whereas at T1 types 1-2 were recorded in only 2.5% of SCL patients. QoL improved in both groups. In the younger group, a significant improvement in QoL was recorded in ARM patients for eight of nine variables and in SCL patients for seven of nine variables. Conclusion: This study showed that Peristeen TAI resulted in a significant time reduction in colonic cleansing, increased independence from the carer and improved QoL in paediatric patients with ARMs and SCLs.
AB - Aim: In paediatric and adult patients with neurogenic bowel, transanal irrigation (TAI) of the colon has gained popularity due to the introduction of a specifically designed device. The aim of this pilot study was to present the results of TAI using the Peristeen® TAI system in a group of paediatric patients with anorectal malformation (ARM) and congenital or acquired spinal cord lesions (SCLs). Method: Eight Italian paediatric surgery and spina bifida centres participated in the study. The inclusion criteria were age between 6 and 17 years, weight above 20 kg and unsatisfactory bowel management. Patients with chronic inflammatory bowel disease, mental disability and surgery within the previous 3 months were excluded. At the beginning of treatment (T0) and after 3 months (T1) the Bristol scale, a questionnaire assessing bowel function, and two questionnaires on quality of life (QoL) for patients aged 6-11 years (CHQ-pf50) and 12-17 years (SF36) were administered. Results: Eighty-three patients were enrolled, and seventy-eight completed the study (41 ARMs, 37 SCLs). At T1, constipation was reduced in ARMs from 69% to 25.6% and in SCLs from 92.7% to 41.5%, faecal incontinence in ARMs from 50% to 18.6% and in SCLs from 39% to 9.8% and flatus incontinence in ARMs from 20.9% to 9.8% and in SCLs from 31.7% to 10%. At T0, the Bristol Stool Scale types were 1-2 in 45% of ARMs and 77.5% of SCL patients, whereas at T1 types 1-2 were recorded in only 2.5% of SCL patients. QoL improved in both groups. In the younger group, a significant improvement in QoL was recorded in ARM patients for eight of nine variables and in SCL patients for seven of nine variables. Conclusion: This study showed that Peristeen TAI resulted in a significant time reduction in colonic cleansing, increased independence from the carer and improved QoL in paediatric patients with ARMs and SCLs.
KW - Anorectal malformation
KW - Bowel dysfunction
KW - Enema
KW - Peristeen
KW - Spinal cord injuries
KW - Transanal irrigation
UR - http://www.scopus.com/inward/record.url?scp=84955453055&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955453055&partnerID=8YFLogxK
U2 - 10.1111/codi.13101
DO - 10.1111/codi.13101
M3 - Article
VL - 18
SP - 86
EP - 93
JO - Colorectal Disease
JF - Colorectal Disease
SN - 1462-8910
IS - 1
ER -