Peritonectomia e chemioipertermia nel trattamento delle carcinosi peritoneali: "learning curve".

Translated title of the contribution: Peritonectomy and chemohyperthermia in the treatment of peritoneal carcinomatosis: learning curve

F. Cavaliere, M. Valle, B. De Rosa, O. Federici, D. Giannarelli, A. Garofalo

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A prospective study has been carried on 37 patients affected by peritoneal carcinomatosis from various primary. Patients have been treated by cytoreductive surgery and intraoperative hyperthermic chemoperfusion. CC 0-1 has been achieved in 81%. The temperature distribution study showed a "barrier effect" with no statistically significant correlation to the survival. Major morbidity and mortality was respectively 37.8% and 16.2%. Two-yr overall survival was 49.1% for all series. Morbidity was significantly directly correlated to the duration of the surgical treatment. A learning curve of 19 months have been observed, after that only one death out 21 procedures has been recorded. Peritoneal carcinomatosis patients, that are submitted to integrated treatment, need a peculiar management that is not comparable to any other in the oncological setting and that requires specific competence.

Translated title of the contributionPeritonectomy and chemohyperthermia in the treatment of peritoneal carcinomatosis: learning curve
Original languageItalian
Title of host publicationI supplementi di Tumori : official journal of Società italiana di cancerologia ... [et al.]
Volume4
Edition3
Publication statusPublished - 2005

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