Abstract
The importance of peroxisomes for human health is highlighted by the number of peroxisomal disorders (PDs), diseases associated to peroxisome biogenesis disorders and peroxisomal enzyme/transporter deficiencies. Currently, many physiological/biosynthetic mechanisms involved in these illnesses have been elucidated, but PDs remain incurable. This review examines the most important aspects concerning peroxisomes (i.e. peroxisome proliferation, peroxisome biogenesis, metabolic functions of mammalian peroxisomes) and presents the most significant trends and advances in the study of peroxisomal disorders.
| Original language | English |
|---|---|
| Pages (from-to) | 615-625 |
| Number of pages | 11 |
| Journal | Experimental and Toxicologic Pathology |
| Volume | 62 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Nov 2010 |
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Keywords
- Peroxisomal Β-oxidation
- Peroxisomal biogenesis
- Peroxisomal disorders
- Peroxisomal metabolism
- Peroxisomes
ASJC Scopus subject areas
- Cell Biology
- Pathology and Forensic Medicine
- Toxicology
Cite this
Peroxisomes and peroxisomal disorders : The main facts. / Fidaleo, Marco.
In: Experimental and Toxicologic Pathology, Vol. 62, No. 6, 11.2010, p. 615-625.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peroxisomes and peroxisomal disorders
T2 - The main facts
AU - Fidaleo, Marco
PY - 2010/11
Y1 - 2010/11
N2 - The importance of peroxisomes for human health is highlighted by the number of peroxisomal disorders (PDs), diseases associated to peroxisome biogenesis disorders and peroxisomal enzyme/transporter deficiencies. Currently, many physiological/biosynthetic mechanisms involved in these illnesses have been elucidated, but PDs remain incurable. This review examines the most important aspects concerning peroxisomes (i.e. peroxisome proliferation, peroxisome biogenesis, metabolic functions of mammalian peroxisomes) and presents the most significant trends and advances in the study of peroxisomal disorders.
AB - The importance of peroxisomes for human health is highlighted by the number of peroxisomal disorders (PDs), diseases associated to peroxisome biogenesis disorders and peroxisomal enzyme/transporter deficiencies. Currently, many physiological/biosynthetic mechanisms involved in these illnesses have been elucidated, but PDs remain incurable. This review examines the most important aspects concerning peroxisomes (i.e. peroxisome proliferation, peroxisome biogenesis, metabolic functions of mammalian peroxisomes) and presents the most significant trends and advances in the study of peroxisomal disorders.
KW - Peroxisomal Β-oxidation
KW - Peroxisomal biogenesis
KW - Peroxisomal disorders
KW - Peroxisomal metabolism
KW - Peroxisomes
UR - http://www.scopus.com/inward/record.url?scp=77957267457&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77957267457&partnerID=8YFLogxK
U2 - 10.1016/j.etp.2009.08.008
DO - 10.1016/j.etp.2009.08.008
M3 - Article
VL - 62
SP - 615
EP - 625
JO - Experimental and Toxicologic Pathology
JF - Experimental and Toxicologic Pathology
SN - 0940-2993
IS - 6
ER -