Peroxisomes and peroxisomal disorders: The main facts

Marco Fidaleo

Research output: Contribution to journalArticle

Abstract

The importance of peroxisomes for human health is highlighted by the number of peroxisomal disorders (PDs), diseases associated to peroxisome biogenesis disorders and peroxisomal enzyme/transporter deficiencies. Currently, many physiological/biosynthetic mechanisms involved in these illnesses have been elucidated, but PDs remain incurable. This review examines the most important aspects concerning peroxisomes (i.e. peroxisome proliferation, peroxisome biogenesis, metabolic functions of mammalian peroxisomes) and presents the most significant trends and advances in the study of peroxisomal disorders.

Original languageEnglish
Pages (from-to)615-625
Number of pages11
JournalExperimental and Toxicologic Pathology
Volume62
Issue number6
DOIs
Publication statusPublished - Nov 2010

Keywords

  • Peroxisomal Β-oxidation
  • Peroxisomal biogenesis
  • Peroxisomal disorders
  • Peroxisomal metabolism
  • Peroxisomes

ASJC Scopus subject areas

  • Cell Biology
  • Pathology and Forensic Medicine
  • Toxicology

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