Persistence of TEM-52/TEM-92 and SHV-12 extended-spectrum β-lactamases in clinical isolates of enterobacteriaceae in Italy

Mariagrazia Perilli, Bernardetta Segatore, Claudia Mugnaioli, Giuseppe Celenza, Gian Maria Rossolini, Stefania Stefani, Francesco Luzzaro, Beatrice Pini, Gianfranco Amicosante

Research output: Contribution to journalArticlepeer-review

Abstract

Extended-spectrum β-lactamases (ESBLs) belonging to the TEM and SHV families were investigated in 583 ESBL-producing Enterobacteriaceae collected at the clinical microbiology laboratories of 11 teaching Italian hospitals. By molecular analysis TEM-type and SHV-type ESBLs were confirmed on 154 and 74 isolates, respectively. High variability was found among TEM-types β-lactamases with the following variants: TEM-5, TEM-6, TEM-12, TEM-15, TEM-24, TEM-26, TEM-29, TEM-52, TEM-92, TEM-134, and TEM-149. Among SHV variants, SHV-2a, SHV-5, SHV-12, and SHV-28 have been detected. The most widespread variants are TEM-52/92 and SHV-12.

Original languageEnglish
Pages (from-to)521-524
Number of pages4
JournalMicrobial Drug Resistance
Volume17
Issue number4
DOIs
Publication statusPublished - Dec 1 2011

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology
  • Immunology
  • Microbiology

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