Persistent blood pressure increase induced by heavy smoking

Antonella Groppelli, Dante Giorgi, Stefano Omboni, Gianfranco Parati, Giuseppe Manciat

Research output: Contribution to journalArticle

Abstract

Objective: To test the hypothesis that heavy smoking is associated with a persistent increase in blood pressure. Design: In 10 normotensive smokers asked to smoke one cigarette every 15 min for 1 h, blood pressure and heart rate were continuously monitored during the smoking period and during the preceding non-smoking hour. In six other normotensive smokers asked to smoke two cigarettes per hour throughout the whole day, blood pressure and heart rate were monitored non-invasively in ambulatory conditions for 8h (0900–1700 h). Blood pressure monitoring was repeated during a non-smoking day. Methods: Beat-to-beat blood pressure and heart rate were monitored at rest by means of the Finapres device. Blood pressure signal was sampled at 165 Hz by a computer to calculate hourly data. Ambulatory blood pressure and heart rate were measured once every 10 min. Results: In resting conditions, the first cigarette caused an immediate and marked increase in blood pressure and heart rate, and the peak blood pressure and heart rate achieved were similar for the remaining three cigarettes. In each instance, the hemodynamic effects were so prolonged that throughout the smoking hour, blood pressure and heart rate were persistently higher than during the non-smoking hour. The standard deviations of systolic and diastolic blood pressure and heart rate were also higher during the smoking hour, indicating an increase in blood pressure and heart rate variability. In the six ambulant smokers, daytime blood pressure and heart rate were also persistently higher during smoking than during non-smoking. Conclusions: Heavy smoking is associated with a persistent rise in blood pressure and also with an increase in blood pressure vari.

Original languageEnglish
Pages (from-to)495-499
Number of pages5
JournalJournal of Hypertension
Volume10
Issue number5
Publication statusPublished - 1992

Keywords

  • Ambulatory blood pressure monitoring
  • Blood pressure variability
  • Cardiovascular risk
  • Continuous blood pressure monitoring
  • Hypertension
  • Smoking

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Internal Medicine
  • Endocrinology

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  • Cite this

    Groppelli, A., Giorgi, D., Omboni, S., Parati, G., & Manciat, G. (1992). Persistent blood pressure increase induced by heavy smoking. Journal of Hypertension, 10(5), 495-499.