Abstract
The heart rate of 11 smokers was collected throughout their first year of abstinence. One day after smoking cessation, we recorded a significant mean heart rate drop of 9.07 beats per min, from 74.18 to 65.11 beats per min. No significant variation was afterwards detected at any chosen time point (week 1, 2, 3, 4, 6, month 3, 6, 12). In fact, 1 year after cessation the mean heart rate was still 66.36 beats per min, well below initial baseline values. These data indicate that the decrease in heart rate following smoking cessation mostly represents a permanent return to individual normal values in the absence of nicotine self-administration. Nonetheless, three subjects did show a trend toward the recovery of their precessation heart rate and one subject fully recovered it between months 3 and 6 of abstinence. This trend suggests that, while heart rate adaptation to nicotine is largely of an acute nature, there may also be a chronic component. Its role, though usually minor, should become detectable in a few subjects, because of wide interindividual variability.
| Original language | English |
|---|---|
| Pages (from-to) | 397-400 |
| Number of pages | 4 |
| Journal | Psychopharmacology |
| Volume | 106 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 1992 |
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Keywords
- Heart rate
- Nicotine tolerance
- Nicotine withdrawal
- Smoking cessation
ASJC Scopus subject areas
- Pharmacology
Cite this
Persistent decrease in heart rate after smoking cessation : A 1-year follow-up study. / Persico, A. M.
In: Psychopharmacology, Vol. 106, No. 3, 03.1992, p. 397-400.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Persistent decrease in heart rate after smoking cessation
T2 - A 1-year follow-up study
AU - Persico, A. M.
PY - 1992/3
Y1 - 1992/3
N2 - The heart rate of 11 smokers was collected throughout their first year of abstinence. One day after smoking cessation, we recorded a significant mean heart rate drop of 9.07 beats per min, from 74.18 to 65.11 beats per min. No significant variation was afterwards detected at any chosen time point (week 1, 2, 3, 4, 6, month 3, 6, 12). In fact, 1 year after cessation the mean heart rate was still 66.36 beats per min, well below initial baseline values. These data indicate that the decrease in heart rate following smoking cessation mostly represents a permanent return to individual normal values in the absence of nicotine self-administration. Nonetheless, three subjects did show a trend toward the recovery of their precessation heart rate and one subject fully recovered it between months 3 and 6 of abstinence. This trend suggests that, while heart rate adaptation to nicotine is largely of an acute nature, there may also be a chronic component. Its role, though usually minor, should become detectable in a few subjects, because of wide interindividual variability.
AB - The heart rate of 11 smokers was collected throughout their first year of abstinence. One day after smoking cessation, we recorded a significant mean heart rate drop of 9.07 beats per min, from 74.18 to 65.11 beats per min. No significant variation was afterwards detected at any chosen time point (week 1, 2, 3, 4, 6, month 3, 6, 12). In fact, 1 year after cessation the mean heart rate was still 66.36 beats per min, well below initial baseline values. These data indicate that the decrease in heart rate following smoking cessation mostly represents a permanent return to individual normal values in the absence of nicotine self-administration. Nonetheless, three subjects did show a trend toward the recovery of their precessation heart rate and one subject fully recovered it between months 3 and 6 of abstinence. This trend suggests that, while heart rate adaptation to nicotine is largely of an acute nature, there may also be a chronic component. Its role, though usually minor, should become detectable in a few subjects, because of wide interindividual variability.
KW - Heart rate
KW - Nicotine tolerance
KW - Nicotine withdrawal
KW - Smoking cessation
UR - http://www.scopus.com/inward/record.url?scp=0026592978&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026592978&partnerID=8YFLogxK
U2 - 10.1007/BF02245425
DO - 10.1007/BF02245425
M3 - Article
C2 - 1570388
AN - SCOPUS:0026592978
VL - 106
SP - 397
EP - 400
JO - Psychopharmacology
JF - Psychopharmacology
SN - 0033-3158
IS - 3
ER -