Persistent decrease in heart rate after smoking cessation: A 1-year follow-up study

A. M. Persico

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The heart rate of 11 smokers was collected throughout their first year of abstinence. One day after smoking cessation, we recorded a significant mean heart rate drop of 9.07 beats per min, from 74.18 to 65.11 beats per min. No significant variation was afterwards detected at any chosen time point (week 1, 2, 3, 4, 6, month 3, 6, 12). In fact, 1 year after cessation the mean heart rate was still 66.36 beats per min, well below initial baseline values. These data indicate that the decrease in heart rate following smoking cessation mostly represents a permanent return to individual normal values in the absence of nicotine self-administration. Nonetheless, three subjects did show a trend toward the recovery of their precessation heart rate and one subject fully recovered it between months 3 and 6 of abstinence. This trend suggests that, while heart rate adaptation to nicotine is largely of an acute nature, there may also be a chronic component. Its role, though usually minor, should become detectable in a few subjects, because of wide interindividual variability.

Original languageEnglish
Pages (from-to)397-400
Number of pages4
JournalPsychopharmacology
Volume106
Issue number3
DOIs
Publication statusPublished - Mar 1992

Fingerprint

Smoking Cessation
Heart Rate
Nicotine
Self Administration
Reference Values

Keywords

  • Heart rate
  • Nicotine tolerance
  • Nicotine withdrawal
  • Smoking cessation

ASJC Scopus subject areas

  • Pharmacology

Cite this

Persistent decrease in heart rate after smoking cessation : A 1-year follow-up study. / Persico, A. M.

In: Psychopharmacology, Vol. 106, No. 3, 03.1992, p. 397-400.

Research output: Contribution to journalArticle

@article{fd54ca7c8fca4f3f8f7d4f6202b20251,
title = "Persistent decrease in heart rate after smoking cessation: A 1-year follow-up study",
abstract = "The heart rate of 11 smokers was collected throughout their first year of abstinence. One day after smoking cessation, we recorded a significant mean heart rate drop of 9.07 beats per min, from 74.18 to 65.11 beats per min. No significant variation was afterwards detected at any chosen time point (week 1, 2, 3, 4, 6, month 3, 6, 12). In fact, 1 year after cessation the mean heart rate was still 66.36 beats per min, well below initial baseline values. These data indicate that the decrease in heart rate following smoking cessation mostly represents a permanent return to individual normal values in the absence of nicotine self-administration. Nonetheless, three subjects did show a trend toward the recovery of their precessation heart rate and one subject fully recovered it between months 3 and 6 of abstinence. This trend suggests that, while heart rate adaptation to nicotine is largely of an acute nature, there may also be a chronic component. Its role, though usually minor, should become detectable in a few subjects, because of wide interindividual variability.",
keywords = "Heart rate, Nicotine tolerance, Nicotine withdrawal, Smoking cessation",
author = "Persico, {A. M.}",
year = "1992",
month = "3",
doi = "10.1007/BF02245425",
language = "English",
volume = "106",
pages = "397--400",
journal = "Psychopharmacology",
issn = "0033-3158",
publisher = "Springer Verlag",
number = "3",

}

TY - JOUR

T1 - Persistent decrease in heart rate after smoking cessation

T2 - A 1-year follow-up study

AU - Persico, A. M.

PY - 1992/3

Y1 - 1992/3

N2 - The heart rate of 11 smokers was collected throughout their first year of abstinence. One day after smoking cessation, we recorded a significant mean heart rate drop of 9.07 beats per min, from 74.18 to 65.11 beats per min. No significant variation was afterwards detected at any chosen time point (week 1, 2, 3, 4, 6, month 3, 6, 12). In fact, 1 year after cessation the mean heart rate was still 66.36 beats per min, well below initial baseline values. These data indicate that the decrease in heart rate following smoking cessation mostly represents a permanent return to individual normal values in the absence of nicotine self-administration. Nonetheless, three subjects did show a trend toward the recovery of their precessation heart rate and one subject fully recovered it between months 3 and 6 of abstinence. This trend suggests that, while heart rate adaptation to nicotine is largely of an acute nature, there may also be a chronic component. Its role, though usually minor, should become detectable in a few subjects, because of wide interindividual variability.

AB - The heart rate of 11 smokers was collected throughout their first year of abstinence. One day after smoking cessation, we recorded a significant mean heart rate drop of 9.07 beats per min, from 74.18 to 65.11 beats per min. No significant variation was afterwards detected at any chosen time point (week 1, 2, 3, 4, 6, month 3, 6, 12). In fact, 1 year after cessation the mean heart rate was still 66.36 beats per min, well below initial baseline values. These data indicate that the decrease in heart rate following smoking cessation mostly represents a permanent return to individual normal values in the absence of nicotine self-administration. Nonetheless, three subjects did show a trend toward the recovery of their precessation heart rate and one subject fully recovered it between months 3 and 6 of abstinence. This trend suggests that, while heart rate adaptation to nicotine is largely of an acute nature, there may also be a chronic component. Its role, though usually minor, should become detectable in a few subjects, because of wide interindividual variability.

KW - Heart rate

KW - Nicotine tolerance

KW - Nicotine withdrawal

KW - Smoking cessation

UR - http://www.scopus.com/inward/record.url?scp=0026592978&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026592978&partnerID=8YFLogxK

U2 - 10.1007/BF02245425

DO - 10.1007/BF02245425

M3 - Article

C2 - 1570388

AN - SCOPUS:0026592978

VL - 106

SP - 397

EP - 400

JO - Psychopharmacology

JF - Psychopharmacology

SN - 0033-3158

IS - 3

ER -