We described a case of an "atypical" form of PPBL in a non-smoker woman suffering from bone marrow involvement by breast cancer with circulating mononucleated polyclonal B-lymphocytes without polyclonal increase in serum IgM and cytogenetic abnormalities. Whether a PPBL may appear as a reaction to a bone marrow involvement of breast cancer or may be a pre-neoplastic entity, preceding the emergence of a predominant clone, is not completely understood. Lately, because of the natural history of PPBL still remain unclear, these patients need to undergo a careful and continued long follow-up.
|Number of pages||4|
|Publication status||Published - 2006|
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