La sindrome della diarrea persistente post-enteritica: «Take an aspirin for your bowel»?

Translated title of the contribution: Persistent post-enteritic diarrhea: «Take an aspirin for your bowel?»

Giuseppe Maggiore, Silvia Caprai, Marco Sciveres, Luca Bertacca

Research output: Contribution to journalArticlepeer-review

Abstract

In developed countries persistent post-enteritic diarrhea is a clinical syndrome including three distinct entities: Chronic non specific diarrhea, usually not associated with failure to thrive; persistent post-enteritic diarrhea, with moderate growth impairment and histological abnormalities; post-infective gut dysfunction, which is likely a component of the irritable bowel syndrome. Animal models of smooth muscle hypercontractility persisting after an acute infection indicate that mediators, such as PGE2, produced by resident cells, actively maintain the persistent changes in the gut during the post-infective status. The reversibility of these functional changes by anti-inflammatory agents provides a basis for the use of anti-inflammatory drugs in patients with post-infective gut disorder.

Translated title of the contributionPersistent post-enteritic diarrhea: «Take an aspirin for your bowel?»
Original languageItalian
Pages (from-to)670-674
Number of pages5
JournalMedico e Bambino
Volume20
Issue number10
Publication statusPublished - Dec 31 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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