Persistent pulmonary hypertension of the newborn refractory to inhaled nitric oxide treated with milrinone: A case report

Chryssoula Tzialla; Rosa Maria Cerbo; Gianfranco Perotti; Mauro Stronati

Persistent pulmonary hypertension of the newborn refractory to inhaled nitric oxide treated with milrinone: A case report

Chryssoula Tzialla, Rosa Maria Cerbo, Gianfranco Perotti, Mauro Stronati

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Current therapy of persistent pulmonary hypertension of the newborn (PPHN) consists of optimal ventilation, hemodynamic support and selective vasodilatation with inhaled nitric oxide (iNO). We present herein a case of PPHN non-responsive to iNO but treated successfully with a combination of iNO and intravenous milrinone, a phosphodiesterase III inhibitor. This case suggests that the drug may be a useful adjunctive treatment in the management of PPHN.

Original language	English
Pages (from-to)	78-80
Number of pages	3
Journal	Turkish Journal of Pediatrics
Volume	52
Issue number	1
Publication status	Published - Jan 2010

Keywords

Milrinone
Newborn
Phosphodiesterase III inhibitor
Pulmonary hypertension

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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