Persistently low cardiac output predicts high mortality in newborns with cardiogenic shock

G. Sabatino, L. A. Ramenghi, A. Verrotti, S. Gerboni, F. Chiarelli

Research output: Contribution to journalArticle

Abstract

Background. Cardiogenic shock is an acute "unstable" state of circulatory dysfunction. Objective. To evaluate the haemodynamic aspects of 45 newborn infants affected by cardiogenic shock, in relation to etiologies and the mortality rate. Design. Retrospective, correlation study of etiologies, mortality rate and haemodynamic measurements by Doppler ultrasound parameters. Patients. 45 newborn infants with cardiogenic shock, Gestational Age (GA) 37 (34-41), Birth Weight (BW) 2750 (1600-3600) g and a control group of 20 neonates [GA 38 (34-40) wks, BW 2960 (1750-3800) g]. Measurements. Left ventricular Cardiac Output (CO) was measured by a duplex scanner with pulsed Doppler and color flow mapping echocardiography in the first 48 hours of life. Results. In healthy newborns CO was 240 mL/min/kg (210-280), in newborns with cardiogenic shock CO was 170 mL/min/kg (130-200), p150 mL/min/kg and only one (6.2% ) died (p150 mL/min/kg died. Conclusions. Our results show that persistently low CO (≤150 mL/min/kg) during the first 48 hours of life, in newborns with cardiogenic shock due to perinatal asphyxia is associated with a significantly higher mortality.

Original languageEnglish
Pages (from-to)28-32
Number of pages5
JournalPanminerva Medica
Volume40
Issue number1
Publication statusPublished - Mar 1998

Keywords

  • Cardiac output low
  • Infant, newborn
  • Mortality
  • Shock, cardiogenic
  • Ultrasonography, Doppler

ASJC Scopus subject areas

  • Medicine(all)

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    Sabatino, G., Ramenghi, L. A., Verrotti, A., Gerboni, S., & Chiarelli, F. (1998). Persistently low cardiac output predicts high mortality in newborns with cardiogenic shock. Panminerva Medica, 40(1), 28-32.