Pervasive developmental disorder and epilepsy due to maternally derived duplication of 15q11-q13

F. Gurrieri, A. Battaglia, L. Torrisi, R. Tancredi, C. Cavallaro, E. Sangiorgi, G. Neri

Research output: Contribution to journalArticle

Abstract

Duplications of chromosome 15 have been reported in individuals with atypical autism, varying degrees of mental retardation, and epilepsy. The authors report the molecular analysis, neurophysiologic, and clinical evaluation of a 12-year-old boy with atypical autism and epilepsy due to a maternally derived 15q11-q13 duplication. Their findings suggest that this chromosomal region harbors genes for autism and possibly for partial epilepsy that may act in a dose-dependent manner.

Original languageEnglish
Pages (from-to)1694-1697
Number of pages4
JournalNeurology
Volume52
Issue number8
Publication statusPublished - May 12 1999

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ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Gurrieri, F., Battaglia, A., Torrisi, L., Tancredi, R., Cavallaro, C., Sangiorgi, E., & Neri, G. (1999). Pervasive developmental disorder and epilepsy due to maternally derived duplication of 15q11-q13. Neurology, 52(8), 1694-1697.