PET/CT imaging in different types of lung cancer: An overview

Valentina Ambrosini, Silvia Nicolini, Paola Caroli, Cristina Nanni, Arianna Massaro, Maria Cristina Marzola, Domenico Rubello, Stefano Fanti

Research output: Contribution to journalArticlepeer-review


Lung cancer (LC) still represents one of the most common tumours in both women and men. PET/CT is a whole-body non-invasive imaging procedure that has been increasingly used for the assessment of LC patients. In particular, PET/CT added value to CT is mainly related to a more accurate staging of nodal and metastatic sites and to the evaluation of the response to therapy. Although the most common PET tracer for LC evaluation is 18F-FDG, new tracers have been proposed for the evaluation of lung neuroendocrine tumours (68Ga-DOTA-peptides, 18F-DOPA) and for the assessment of central nervous system metastasis (11C-methionine). This review focuses on the main clinical applications and accuracy of PET/CT for the detection of non-small cells lung cancer (NSCLC), broncho-alveolar carcinoma (BAC), small cells lung cancer (SCLC), lung neuroendocrine tumours (NET) and solitary pulmonary nodules (SPN).

Original languageEnglish
Pages (from-to)988-1001
Number of pages14
JournalEuropean Journal of Radiology
Issue number5
Publication statusPublished - May 2012


  • 18F-DOPA
  • 18F-FDG
  • 68Ga-DOTA-peptides
  • Drawbacks
  • Indications
  • Lung cancer
  • PET/CT
  • Various types

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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