Peutz-Jeghers-like melanotic macules associated with esophageal adenocarcinoma

A. Eng, A. Armin, M. Massa, R. Gradini

Research output: Contribution to journalArticlepeer-review


A 67-year-old white man with esophageal adenocarcinoma presented with Peutz-Jeghers-like macules on the lips, face, nipples, and rectal mucosa. Pathological examination of the macules showed atypical melanocytes in the epidermis. The pleomorphic large melanocytes resembled the neoplastic cells seen in melanoma in situ. This is the first report of proliferation of atypical melanocytes in Peutz-Jeghers-like melanosis associated with a primary esophageal adenocarcinoma.

Original languageEnglish
Pages (from-to)152-157
Number of pages6
JournalAmerican Journal of Dermatopathology
Issue number2
Publication statusPublished - 1991


  • Esophageal carcinoma
  • Paraneoplastic syndrome
  • Peutz-Jeghers-like macules

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine


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