Abstract
Introduction: Although heavily investigated over the last decades, Peyronie's disease (PD) pathogenesis remains unclear. Aim: We sought to investigate the association between PD and autoimmune diseases (ADs) in men seeking medical help for sexual dysfunction in the real-life setting. Methods: Complete sociodemographic and clinical data from a homogenous cohort of 1,140 consecutive Caucasian-European men were analyzed. Health-significant comorbidities were scored with the Charlson Comorbidity Index and ADs were stratified according to International Classification of Diseases, Ninth Revision classification. Main Outcome Measures: Descriptive statistics and multivariate logistic regression models tested the association between ADs and PD. Results: PD was diagnosed in 148 (13%) of the 1,140 men; of PD patients, 14 (9.5%) had a comorbid AD; conversely, the rate of ADs in non-PD patients was significantly lower (χ2=24.7; P
| Original language | English |
|---|---|
| Pages (from-to) | 1062-1069 |
| Number of pages | 8 |
| Journal | Journal of Sexual Medicine |
| Volume | 12 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 1 2015 |
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Keywords
- Autoimmune Disease
- Peyronie's Disease
- Psoriasis
- Sexual Dysfunction
ASJC Scopus subject areas
- Urology
- Obstetrics and Gynaecology
- Reproductive Medicine
- Medicine(all)
Cite this
Peyronie's disease and autoimmunity-a real-life clinical study and comprehensive review. / Ventimiglia, Eugenio; Capogrosso, Paolo; Colicchia, Michele; Boeri, Luca; Serino, Alessandro; La Croce, Giovanni; Russo, Andrea; Capitanio, Umberto; Briganti, Alberto; Cantiello, Francesco; Mirone, Vincenzo; Damiano, Rocco; Montorsi, Francesco; Salonia, Andrea.
In: Journal of Sexual Medicine, Vol. 12, No. 4, 01.04.2015, p. 1062-1069.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peyronie's disease and autoimmunity-a real-life clinical study and comprehensive review
AU - Ventimiglia, Eugenio
AU - Capogrosso, Paolo
AU - Colicchia, Michele
AU - Boeri, Luca
AU - Serino, Alessandro
AU - La Croce, Giovanni
AU - Russo, Andrea
AU - Capitanio, Umberto
AU - Briganti, Alberto
AU - Cantiello, Francesco
AU - Mirone, Vincenzo
AU - Damiano, Rocco
AU - Montorsi, Francesco
AU - Salonia, Andrea
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Introduction: Although heavily investigated over the last decades, Peyronie's disease (PD) pathogenesis remains unclear. Aim: We sought to investigate the association between PD and autoimmune diseases (ADs) in men seeking medical help for sexual dysfunction in the real-life setting. Methods: Complete sociodemographic and clinical data from a homogenous cohort of 1,140 consecutive Caucasian-European men were analyzed. Health-significant comorbidities were scored with the Charlson Comorbidity Index and ADs were stratified according to International Classification of Diseases, Ninth Revision classification. Main Outcome Measures: Descriptive statistics and multivariate logistic regression models tested the association between ADs and PD. Results: PD was diagnosed in 148 (13%) of the 1,140 men; of PD patients, 14 (9.5%) had a comorbid AD; conversely, the rate of ADs in non-PD patients was significantly lower (χ2=24.7; P
AB - Introduction: Although heavily investigated over the last decades, Peyronie's disease (PD) pathogenesis remains unclear. Aim: We sought to investigate the association between PD and autoimmune diseases (ADs) in men seeking medical help for sexual dysfunction in the real-life setting. Methods: Complete sociodemographic and clinical data from a homogenous cohort of 1,140 consecutive Caucasian-European men were analyzed. Health-significant comorbidities were scored with the Charlson Comorbidity Index and ADs were stratified according to International Classification of Diseases, Ninth Revision classification. Main Outcome Measures: Descriptive statistics and multivariate logistic regression models tested the association between ADs and PD. Results: PD was diagnosed in 148 (13%) of the 1,140 men; of PD patients, 14 (9.5%) had a comorbid AD; conversely, the rate of ADs in non-PD patients was significantly lower (χ2=24.7; P
KW - Autoimmune Disease
KW - Peyronie's Disease
KW - Psoriasis
KW - Sexual Dysfunction
UR - http://www.scopus.com/inward/record.url?scp=84926352133&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84926352133&partnerID=8YFLogxK
U2 - 10.1111/jsm.12825
DO - 10.1111/jsm.12825
M3 - Article
C2 - 25630575
AN - SCOPUS:84926352133
VL - 12
SP - 1062
EP - 1069
JO - Journal of Sexual Medicine
JF - Journal of Sexual Medicine
SN - 1743-6095
IS - 4
ER -