Phagocyte activation in coronary artery disease

Giovanni Ricevuti, Antonino Mazzone, Iolanda Mazzucchelli, Gianluca Fossati, Davide Pasotti, Paola Cavigliano, Laura Rolandi, Gianluca Viarengo, Marco Rossi, Antonia Notario

Research output: Contribution to journalArticlepeer-review


Recent studies suggest that granulocytes (PMNs) play a role in the pathogenesis of acute and chronic myocardial ischemia and extension of myocardial injury. Granulocytes can release a variety of molecules mediating tissue injury which act synergistically with other molecules and cells. The aim of our investigation was to evaluate the granulocyte function in patients affected by coronary artery disease (CAD) and during coronary angioplasty (PTCA). We studied 20 patients suffering from CAD. The PMN's aggregating activity was greater in the coronary sinus than in the aorta (P4 (P

Original languageEnglish
Pages (from-to)271-278
Number of pages8
JournalFEMS Microbiology Letters
Issue number5-6
Publication statusPublished - 1992


  • Angioplasty
  • Coronary artery disease
  • Integrin
  • Leukotriene
  • Phagocyte

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Microbiology
  • Immunology
  • Microbiology (medical)


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