Pharmaceutical Industries Air Quality

E. Oddone, S. Negri, F. Morandi, M. Imbriani

Research output: Contribution to journalArticle

Abstract

Active pharmaceutical ingredients (APIs) could be risk factors for workers exposed in pharmaceutical industries. Indeed, APIs are compounds specifically designed to interact with human organism and to modify its functioning, and some of them could act as carcinogens or sensitisers, for whom a safe threshold cannot be easily determined. Inhalation is the most important route of exposure.Occupational exposure limits are needed to protect workers' health, both concerning APIs and pharmaceutical intermediates. To date, several approaches have been suggested to set acceptable daily exposure limits in pharmaceutical industries, and they are a key point especially for carcinogens, sensitisers or endocrine disruptors.Despite literature evidence is sparse, occupational risks in pharmaceutical industries cannot be disregarded; several adverse health effects have been observed.In recent years, the quality of air in pharmaceutical industries has improved, even though a special attention has to be paid to exposures to carcinogens and sensitisers.

Original languageEnglish
JournalComprehensive Analytical Chemistry
DOIs
Publication statusAccepted/In press - 2016

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Keywords

  • Air quality
  • Environmental monitoring
  • Occupational exposures
  • Pharmaceutical industry
  • Risk assessment

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

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