Pharmacokinetic interactions between statins and fibrates

Alberto Corsini, Stefano Bellosta, Michael H. Davidson

Research output: Contribution to journalArticle

Abstract

Concomitant use of a fibrate and a statin may offer a therapeutic advantage to patients with dyslipidemia, especially in patients whose low-density lipoprotein cholesterol is controlled by statins but whose high-density lipoprotein cholesterol or triglycerides, or both, are not within goal. However, concern about drug-drug interactions may preclude optimal use of combination statin-fibrate therapy. This article reviews the pharmacokinetics between statins and fibrates, addressing risks associated with drug-drug interactions and combination therapy.

Original languageEnglish
JournalThe American Journal of Cardiology
Volume96
Issue number9 SUPPL. 1
DOIs
Publication statusPublished - Nov 7 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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