Pharmacokinetics and pharmacodynamics: The role of sex and gender

Flavia Franconi, Manuela Sanna, Elisabetta Straface, Roberto Chessa, Giuseppe Rosano

Research output: Chapter in Book/Report/Conference proceedingChapter


In the last years, the attention versus the influence of sex/gender in the drug response largely increased. Since 2001, the Institute of Medicine indicates that sex matters, that is, being male or female is an important basic human variable that should be considered when designing and analyzing studies in all areas and at all levels of ⋯ health-related research.1 Generally, the FDA does not attempt to determine why men are different from women and refers to any identified difference as a gender difference.2

Original languageEnglish
Title of host publicationSex and Gender Aspects in Clinical Medicine
PublisherSpringer-Verlag London Ltd
Number of pages12
ISBN (Print)9780857298324, 0857298313, 9780857298317
Publication statusPublished - Nov 1 2013

ASJC Scopus subject areas

  • Medicine(all)


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