Pharmacokinetics of Cyclophosphamide after prolonged low dose treatment in ovarian cancer patients

M. D'incalci, T. Facchinetti, G. Bolis, C. Mangioni, L. Morasca

Research output: Contribution to journalArticlepeer-review

Abstract

We have studied Cyclophosphamide (Cy) pharmacokinetics in 9 patients after their first intravenous dose of 100 mg, and in 9 patients after 6-13 months of continual treatment with the same dose every day. The half-life of Cy was shorter (p <0.05) in the latter group, the Co was greater (

Original languageEnglish
Pages (from-to)83-85
Number of pages3
JournalEuropean Journal of Drug Metabolism and Pharmacokinetics
Volume4
Issue number2
DOIs
Publication statusPublished - Apr 1979

Keywords

  • Cyclophosphamide
  • Ovarian Cancer
  • Pharmacokinetics

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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