Pharmacological treatment of chronic heart failure

Rachele Adorisio, Leonardo De Luca, Joseph Rossi, Mihai Gheorghiade

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Pharmacological treatment, as it stands today, is a combination of preventive and symptomatic strategies. The mainstay life-saving drugs are angiotensin-converting enzyme inhibitors and β-blockers. Additional benefits are obtained when angiotensin-receptor blockers or aldosterone antagonists are added. Digitalis and/or diuretics are useful for symptom reduction. In addition, combination therapy with hydralazine and isosorbide dinitrate is recommended in African Americans.

Original languageEnglish
Pages (from-to)109-123
Number of pages15
JournalHeart Failure Reviews
Volume11
Issue number2
DOIs
Publication statusPublished - Jun 2006

Fingerprint

Heart Failure
Angiotensin Receptor Antagonists
Pharmacology
Mineralocorticoid Receptor Antagonists
Isosorbide Dinitrate
Hydralazine
Western World
Digitalis
Angiotensin-Converting Enzyme Inhibitors
Diuretics
African Americans
Epidemiology
Therapeutics
Morbidity
Mortality
Pharmaceutical Preparations

Keywords

  • β-blockers
  • Angiotensin-converting enzyme inhibitors
  • Digitalis
  • Diuretics
  • Drugs
  • Heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Pharmacological treatment of chronic heart failure. / Adorisio, Rachele; De Luca, Leonardo; Rossi, Joseph; Gheorghiade, Mihai.

In: Heart Failure Reviews, Vol. 11, No. 2, 06.2006, p. 109-123.

Research output: Contribution to journalArticle

Adorisio, Rachele ; De Luca, Leonardo ; Rossi, Joseph ; Gheorghiade, Mihai. / Pharmacological treatment of chronic heart failure. In: Heart Failure Reviews. 2006 ; Vol. 11, No. 2. pp. 109-123.
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