Abstract
Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Pharmacological treatment, as it stands today, is a combination of preventive and symptomatic strategies. The mainstay life-saving drugs are angiotensin-converting enzyme inhibitors and β-blockers. Additional benefits are obtained when angiotensin-receptor blockers or aldosterone antagonists are added. Digitalis and/or diuretics are useful for symptom reduction. In addition, combination therapy with hydralazine and isosorbide dinitrate is recommended in African Americans.
| Original language | English |
|---|---|
| Pages (from-to) | 109-123 |
| Number of pages | 15 |
| Journal | Heart Failure Reviews |
| Volume | 11 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 2006 |
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Keywords
- β-blockers
- Angiotensin-converting enzyme inhibitors
- Digitalis
- Diuretics
- Drugs
- Heart failure
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Pharmacological treatment of chronic heart failure. / Adorisio, Rachele; De Luca, Leonardo; Rossi, Joseph; Gheorghiade, Mihai.
In: Heart Failure Reviews, Vol. 11, No. 2, 06.2006, p. 109-123.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pharmacological treatment of chronic heart failure
AU - Adorisio, Rachele
AU - De Luca, Leonardo
AU - Rossi, Joseph
AU - Gheorghiade, Mihai
PY - 2006/6
Y1 - 2006/6
N2 - Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Pharmacological treatment, as it stands today, is a combination of preventive and symptomatic strategies. The mainstay life-saving drugs are angiotensin-converting enzyme inhibitors and β-blockers. Additional benefits are obtained when angiotensin-receptor blockers or aldosterone antagonists are added. Digitalis and/or diuretics are useful for symptom reduction. In addition, combination therapy with hydralazine and isosorbide dinitrate is recommended in African Americans.
AB - Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Pharmacological treatment, as it stands today, is a combination of preventive and symptomatic strategies. The mainstay life-saving drugs are angiotensin-converting enzyme inhibitors and β-blockers. Additional benefits are obtained when angiotensin-receptor blockers or aldosterone antagonists are added. Digitalis and/or diuretics are useful for symptom reduction. In addition, combination therapy with hydralazine and isosorbide dinitrate is recommended in African Americans.
KW - β-blockers
KW - Angiotensin-converting enzyme inhibitors
KW - Digitalis
KW - Diuretics
KW - Drugs
KW - Heart failure
UR - http://www.scopus.com/inward/record.url?scp=33747892889&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33747892889&partnerID=8YFLogxK
U2 - 10.1007/s10741-006-9482-z
DO - 10.1007/s10741-006-9482-z
M3 - Article
VL - 11
SP - 109
EP - 123
JO - Heart Failure Reviews
JF - Heart Failure Reviews
SN - 1382-4147
IS - 2
ER -