Pharmacoprevention for hereditary breast and ovarian cancer

Research output: Contribution to journalReview articlepeer-review

Abstract

Hereditary breast and ovarian cancer (HBOC) syndrome is an important women's health condition characterized by an increased susceptibility to the development of cancer, in particular breast and ovarian neoplasms, and is caused by an inherited germline genetic mutation in one or both tumor suppressor genes named BRCA1 and BRCA2. This monographic issue provides an update on our knowledge of this syndrome with particular emphasis on the risk reduction strategies through a pharmacopreventive approach.

Original languageEnglish
Pages (from-to)517-535
Number of pages19
JournalMinerva Ginecologica
Volume68
Issue number5
Publication statusPublished - Oct 1 2016

Keywords

  • Chemoprevention
  • Germ-line mutation
  • Hereditary breast and ovarian cancer syndrome

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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