Pharmacotherapy of intraocular pressure part II. Carbonic anhydrase inhibitors, prostaglandin analogues and prostamides

Ciro Costagliola, Roberto Dell'Omo, Mario R. Romano, Michele Rinaldi, Lucia Zeppa, Francesco Parmeggiani

Research output: Contribution to journalArticlepeer-review

Abstract

The second part of this two part review (please see Expert Opinion on Pharmacotherapy 10(16)) reports the characteristics of other antiglaucoma medications: systemic (acetazomide) and topical (dorzolamide and brinzolamide) carbonic anhydrase inhibitors, which suppress aqueous humour formation; and prostaglandin analogues (latanoprost and travoprost) and prostamides (bimatoprost), which raise aqueous humour outflow. The pharmacologic properties of each compound and its efficacy in the medical treatment of glaucoma, mainly the primary open-angle form, are discussed briefly, focusing on the clinical evidence supporting their use.

Original languageEnglish
Pages (from-to)2859-2870
Number of pages12
JournalExpert Opinion on Pharmacotherapy
Volume10
Issue number17
DOIs
Publication statusPublished - Dec 2009

Keywords

  • Acetazolamide
  • Bimatoprost
  • Brinzolamide
  • Carbonic anhydrase inhibitors
  • Dorzolamide
  • Glaucoma
  • Latanoprost
  • Prostaglandin analogues
  • Prostamides
  • Travoprost

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology

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