Pharyngocutaneous fistula as a complication of total laryngectomy: Review of the literature and analysis of case records

Andrea L. Cavalot, C. Fernando Gervasio, Giuseppe Nazionale, Roberto Albera, Mario Bussi, Alberto Staffieri, V. Ferrero, G. Cortesina

Research output: Contribution to journalArticlepeer-review

Abstract

Pharyngocutaneous fistula is the most common complication of total laryngectomy. The management of this problem increases hospitalization time and delays initiation of postoperative radiotherapy, where indicated. To identify factors predisposing to the development of pharyngocutaneous fistula, we reviewed the postoperative courses of 293 patients who underwent total laryngectomy at our clinic. General factors taken into account were concurrent diseases such as diabetes, liver diseases, or chronic anemia; local factors included radiotherapy before and after surgery, preoperative tracheostomy, type of cervical lymph node removal, and method of pharyngeal closure. We then compared our data with those reported in the literature by other authors. Last, we applied the Fisher exact test to a correlation we found between the higher incidence of fistula in patients with diabetes, liver diseases, or anemia. The local factor that turned out to be statistically most significant for the development of fistula was preoperative radiotherapy.

Original languageEnglish
Pages (from-to)587-592
Number of pages6
JournalOtolaryngology - Head and Neck Surgery
Volume123
Issue number5
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Otorhinolaryngology

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