Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study)

C. Pinto; F. Di Fabio; E. Maiello; S. Pini; T. Latiano; C. Aschele; C. Garufi; A. Bochicchio; G. Rosati; G. Aprile; S. Giaquinta; V. Torri; A. Bardelli; M. Gion; A. Martoni

doi:10.1093/annonc/mdq782

Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study)

C. Pinto, F. Di Fabio, E. Maiello, S. Pini, T. Latiano, C. Aschele, C. Garufi, A. Bochicchio, G. Rosati, G. Aprile, S. Giaquinta, V. Torri, A. Bardelli, M. Gion, A. Martoni

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The aim of this phase II study was to assess the activity of panitumumab in combination with oxaliplatin, 5-fluorouracil, and external radiotherapy (RT) as preoperative treatment in locally advanced rectal cancer patients. Patients and methods: Patients had rectal adenocarcinoma, cT3N+ or cT4N2/+ stage, located

Original language	English
Pages (from-to)	2424-2430
Number of pages	7
Journal	Annals of Oncology
Volume	22
Issue number	11
DOIs	https://doi.org/10.1093/annonc/mdq782
Publication status	Published - Nov 2011

Keywords

5-fluorouracil
Chemoradiotherapy
Oxaliplatin
Panitumumab
Radiotherapy
Rectal cancer

ASJC Scopus subject areas

Oncology
Hematology

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10.1093/annonc/mdq782

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Pinto, C., Di Fabio, F., Maiello, E., Pini, S., Latiano, T., Aschele, C., Garufi, C., Bochicchio, A., Rosati, G., Aprile, G., Giaquinta, S., Torri, V., Bardelli, A., Gion, M., & Martoni, A. (2011). Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study). Annals of Oncology, 22(11), 2424-2430. https://doi.org/10.1093/annonc/mdq782

Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study). / Pinto, C.; Di Fabio, F.; Maiello, E.; Pini, S.; Latiano, T.; Aschele, C.; Garufi, C.; Bochicchio, A.; Rosati, G.; Aprile, G.; Giaquinta, S.; Torri, V.; Bardelli, A.; Gion, M.; Martoni, A.

In: Annals of Oncology, Vol. 22, No. 11, 11.2011, p. 2424-2430.

Research output: Contribution to journal › Article › peer-review

Pinto, C, Di Fabio, F, Maiello, E, Pini, S, Latiano, T, Aschele, C, Garufi, C, Bochicchio, A, Rosati, G, Aprile, G, Giaquinta, S, Torri, V , Bardelli, A, Gion, M & Martoni, A 2011, 'Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study)', Annals of Oncology, vol. 22, no. 11, pp. 2424-2430. https://doi.org/10.1093/annonc/mdq782

Pinto, C. ; Di Fabio, F. ; Maiello, E. ; Pini, S. ; Latiano, T. ; Aschele, C. ; Garufi, C. ; Bochicchio, A. ; Rosati, G. ; Aprile, G. ; Giaquinta, S. ; Torri, V. ; Bardelli, A. ; Gion, M. ; Martoni, A. / Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study). In: Annals of Oncology. 2011 ; Vol. 22, No. 11. pp. 2424-2430.

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AU - Aprile, G.

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