Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study)

C. Pinto; F. Di Fabio; E. Maiello; S. Pini; T. Latiano; C. Aschele; C. Garufi; A. Bochicchio; G. Rosati; G. Aprile; S. Giaquinta; V. Torri; A. Bardelli; M. Gion; A. Martoni

doi:10.1093/annonc/mdq782

Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study)

C. Pinto, F. Di Fabio, E. Maiello, S. Pini, T. Latiano, C. Aschele, C. Garufi, A. Bochicchio, G. Rosati, G. Aprile, S. Giaquinta, V. Torri, A. Bardelli, M. Gion, A. Martoni

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The aim of this phase II study was to assess the activity of panitumumab in combination with oxaliplatin, 5-fluorouracil, and external radiotherapy (RT) as preoperative treatment in locally advanced rectal cancer patients. Patients and methods: Patients had rectal adenocarcinoma, cT3N+ or cT4N2/+ stage, located

Original language	English
Pages (from-to)	2424-2430
Number of pages	7
Journal	Annals of Oncology
Volume	22
Issue number	11
DOIs	https://doi.org/10.1093/annonc/mdq782
Publication status	Published - Nov 2011

Keywords

5-fluorouracil
Chemoradiotherapy
Oxaliplatin
Panitumumab
Radiotherapy
Rectal cancer

ASJC Scopus subject areas

Oncology
Hematology

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Pinto, C., Di Fabio, F., Maiello, E., Pini, S., Latiano, T., Aschele, C., Garufi, C., Bochicchio, A., Rosati, G., Aprile, G., Giaquinta, S., Torri, V., Bardelli, A., Gion, M., & Martoni, A. (2011). Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study). Annals of Oncology, 22(11), 2424-2430. https://doi.org/10.1093/annonc/mdq782

Pinto, C, Di Fabio, F, Maiello, E, Pini, S, Latiano, T, Aschele, C, Garufi, C, Bochicchio, A, Rosati, G, Aprile, G, Giaquinta, S, Torri, V , Bardelli, A, Gion, M & Martoni, A 2011, 'Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study)', Annals of Oncology, vol. 22, no. 11, pp. 2424-2430. https://doi.org/10.1093/annonc/mdq782

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AU - Di Fabio, F.

AU - Maiello, E.

AU - Pini, S.

AU - Latiano, T.

AU - Aschele, C.

AU - Garufi, C.

AU - Bochicchio, A.

AU - Rosati, G.

AU - Aprile, G.

AU - Giaquinta, S.

AU - Torri, V.

AU - Bardelli, A.

AU - Gion, M.

AU - Martoni, A.

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KW - Panitumumab

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Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (starpan/STAR-02 Study)

Abstract

Keywords

ASJC Scopus subject areas

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