In this study 24 patients with metastatic cervical cancer were treated with a weekly bolus injection of 4′-epidoxorubicin at a dose of 12.5 mg/m2. All patients were followed until disease progression. Toxicity was generally absent or very mild. Only 1 patient (4%) had a partial remission lasting 23 weeks and 9 patients (38%) had stable disease with a median duration of 13 weeks (range 7-36). 4′-Epidoxorubicin at this dose and schedule is not active in metastatic squamous cell carcinoma of the cervix.
ASJC Scopus subject areas
- Cancer Research