Phenylketonuria: Diet for life or not?

R. Cerone; M. C. Schiaffino; S. Di Stefano; E. Veneselli

doi:10.1080/08035259950169350

Phenylketonuria: Diet for life or not?

R. Cerone, M. C. Schiaffino, S. Di Stefano, E. Veneselli

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

In order to evaluate the argument whether or not a restricted phenylalanine diet should be maintained for life in patients with phenylketonuria (PKU), 16 patients with early treated PKU but off diet since their 11th birthday were investigated. The evaluation included a detailed neurological examination, IQ, neurophysiological testing and MRI of the brain. Even if IQ and electrophysiological studies were normal or unchanged if compared to results before diet discontinuation, all patients revealed abnormal neurological signs. We conclude that the diet should be continued during adult life, but somewhat higher phenylalanine levels (

Original language	English
Pages (from-to)	664-666
Number of pages	3
Journal	Acta Paediatrica, International Journal of Paediatrics
Volume	88
Issue number	6
DOIs	https://doi.org/10.1080/08035259950169350
Publication status	Published - Jun 1999

Keywords

Adolescence
Dietary treatment
Phenylketonuria

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1080/08035259950169350

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AU - Di Stefano, S.

AU - Veneselli, E.

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AB - In order to evaluate the argument whether or not a restricted phenylalanine diet should be maintained for life in patients with phenylketonuria (PKU), 16 patients with early treated PKU but off diet since their 11th birthday were investigated. The evaluation included a detailed neurological examination, IQ, neurophysiological testing and MRI of the brain. Even if IQ and electrophysiological studies were normal or unchanged if compared to results before diet discontinuation, all patients revealed abnormal neurological signs. We conclude that the diet should be continued during adult life, but somewhat higher phenylalanine levels (

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Phenylketonuria: Diet for life or not?

Abstract

Keywords

ASJC Scopus subject areas

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