Phenytoin-induced increase in growth hormone response to levodopa in adult males

R. D'Alessandro, P. Cortelli, R. Gallassi, E. Ghisoli, N. Montanaro, E. Zoni, A. Baruzzi

Research output: Contribution to journalArticlepeer-review

Abstract

Growth hormone and prolactin response to levodopa were evaluated before and after long-term phenytoin treatment in five men with previously untreated partial epilepsy. After phenytoin treatment, growth hormone response to levodopa increased. There was a close relationship between growth hormone response to levodopa and plasma phenytoin concentrations. These findings suggest a phenytoin-induced dopaminergic activity at the hypothalamic-pituitary level in adult males.

Original languageEnglish
Pages (from-to)715-719
Number of pages5
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume47
Issue number7
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health

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