Abstract
The effect of viloxazine (VLX) on plasma levels of phenytoin (PHT) was evaluated in a group of 10 epileptic patients stabilized on PHT monotherapy. Addition of VLX induced an increase in PHT levels of 37,3% on average and caused the onset of PHT toxicity in 4 pts, who had to discontinue VLX before the established time. These data suggest that VLX inhibits PHT methabolism.
| Original language | Italian |
|---|---|
| Pages (from-to) | 379-380 |
| Number of pages | 2 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Issue number | 70-71 |
| Publication status | Published - 1990 |
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ASJC Scopus subject areas
- Clinical Neurology
Cite this
Pisani, F., Oteri, G., Caputo, M., Artesi, C., Russo, M., Trio, R., & Perucca, E. (1990). INTERAZIONE FENITOINA-VILOXAZINA IN PAZIENTI CON EPILESSIA. Bollettino - Lega Italiana contro l'Epilessia, (70-71), 379-380.