INTERAZIONE FENITOINA-VILOXAZINA IN PAZIENTI CON EPILESSIA

Translated title of the contribution: Phenytoin-viloxazine interaction in patients with epilepsy

F. Pisani, G. Oteri, M. Caputo, C. Artesi, M. Russo, R. Trio, E. Perucca

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of viloxazine (VLX) on plasma levels of phenytoin (PHT) was evaluated in a group of 10 epileptic patients stabilized on PHT monotherapy. Addition of VLX induced an increase in PHT levels of 37,3% on average and caused the onset of PHT toxicity in 4 pts, who had to discontinue VLX before the established time. These data suggest that VLX inhibits PHT methabolism.

Translated title of the contributionPhenytoin-viloxazine interaction in patients with epilepsy
Original languageItalian
Pages (from-to)379-380
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number70-71
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Clinical Neurology

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