Abstract
The effect of viloxazine (VLX) on plasma levels of phenytoin (PHT) was evaluated in a group of 10 epileptic patients stabilized on PHT monotherapy. Addition of VLX induced an increase in PHT levels of 37,3% on average and caused the onset of PHT toxicity in 4 pts, who had to discontinue VLX before the established time. These data suggest that VLX inhibits PHT methabolism.
| Translated title of the contribution | Phenytoin-viloxazine interaction in patients with epilepsy |
|---|---|
| Original language | Italian |
| Pages (from-to) | 379-380 |
| Number of pages | 2 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Issue number | 70-71 |
| Publication status | Published - 1990 |
ASJC Scopus subject areas
- Clinical Neurology