Phosphoryl-EZH-ion

Giuseppina Caretti, Daniela Palacios, Vittorio Sartorelli, Pier Lorenzo Puri

Research output: Contribution to journalArticlepeer-review

Abstract

Polycomb group (PcG) proteins regulate gene expression in embryonic and adult stem cells, but the mechanisms responsible for PcG gene targeting and regulation remain largely unknown. Recent evidence shows that EZH2, the enzymatic subunit of Polycomb Repressive Complex 2 (PRC2), is a nuclear phosphoprotein linking cell-cycle-intrinsic or extracellular signals to specific epigenetic signatures.

Original languageEnglish
Pages (from-to)262-265
Number of pages4
JournalCell Stem Cell
Volume8
Issue number3
DOIs
Publication statusPublished - Mar 4 2011

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Medicine
  • Genetics

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