Photodynamic therapy increases the eligibility for feeder vessel treatment of choroidal neovascularization caused by age-related macular degeneration

Stefano Piermarocchi, Giuseppe Lo Giudice, Mauro Sartore, Federico Friede, Tatiana Segato, Elisabetta Pilotto, Edoardo Midena

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: To report angiographic observations about feeder vessel identification after photodynamic therapy in patients with choroidal neovascularization caused by age-related macular degeneration. DESIGN: Cohort study. METHODS: We analyzed fluorescein and indocyanine green dynamic angiography in 156 eyes of 145 patients before and after photodynamic therapy to identify the feeder vessels of the choroidal neovascular membrane. RESULTS: Before photodynamic therapy one or more feeder vessel could be detected in 35 (22.4%) out of 156 eyes with choroidal neovascularization. Three months after photodynamic therapy, a feeder vessel could be identified in 112 (84.2%) out of 133 eyes with persistent choroidal neovascularization. Among these, 16 eyes received direct laser photocoagulation of the feeder vessel and did not need any further photodynamic therapy. CONCLUSION: Previous photodynamic therapy improves the detection of the feeder vessel of the choroidal neovascularization. A sequential combined therapy (photodynamic and feeder vessel treatment) could be considered as an alternative to multiple photodynamic treatments.

Original languageEnglish
Pages (from-to)572-575
Number of pages4
JournalAmerican Journal of Ophthalmology
Volume133
Issue number4
DOIs
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Ophthalmology

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