Risposta fotoparossistica in età precoce: Studio retrospettivo di 43 pazienti

We reviewed the clinical charts and EEGs, involving phtostimolation, of 6612 consecutive patients aged 0-5 years observed between 1993 and 2008 at the National Neurological Institut in Milan. We found abnormal EEG response to IPS in 43 out of 6612 patients (0,65%). In half of the cases the patients were affected by pathological condition, in which the presence of PPRs is well known and expected: idiopathic epilepsies, severe myoclonic epilepsy of infancy and degenerative disorders. In the remaining 50% of cases, the IPS was observed in patients affected by stattic encephalopathies, including cerebral palsy, cortical malformation, and neurocutaneous diseases. A subgroup of patients was affected by a non progressive disease, of unknown etiology characterized by mental retardation, dismorphic features, and seizures.